The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10917 malaria professionals are enjoying the free benefits of MalariaWorld today

plasmodium sp.

NOT Open Access | Structural and immunogenicity analysis of reconstructed ancestral and consensus P48/45 for cross-species anti malaria transmission-blocking vaccine

June 9, 2021 - 14:16 -- NOT Open Access
Author(s): 
Ramanto KN, Nurdiansyah R
Reference: 
Comput Biol Chem. 2021 Jun;92:107495

The development of the anti-malaria vaccine holds a promising future in malaria control. One of the anti-malaria vaccine strategies known as the transmission-blocking vaccine (TBV) is to inhibit the parasite transmission between humans and mosquitoes by targeting the parasite gametocyte. Previously, we found that P48/45 included in the 6-Cysteine protein family shared by Plasmodium sp. We also detected vaccine properties possessed by all human-infecting Plasmodium and could be used as a cross-species anti-malaria vaccine.

NOT Open Access | Immunogenicity and structural efficacy of P41 of Plasmodium sp. as potential cross-species blood-stage malaria vaccine

June 9, 2021 - 14:14 -- NOT Open Access
Author(s): 
Ramanto KN, Nurdiansyah R
Reference: 
Comput Biol Chem. 2021 Jun;92:107493

Vaccine based strategies offer a promising future in malaria control by generating protective immunity against natural infection. However, vaccine development is hindered by the Plasmodium sp. genetic diversity. Previously, we have shown P41 protein from 6-Cysteine shared by Plasmodium sp. and could be used for cross-species anti-malaria vaccines.

Not Open Access | C-terminal aromatic residue of Plasmodium ferredoxin important for the interaction with ferredoxin:NADP(H) oxidoreductase: possible involvement for artemisinin resistance of human malaria parasites

June 1, 2020 - 16:48 -- NOT Open Access
Author(s): 
Kimata-Ariga Y, Sakamoto A, Kamatani M, Saitoh T, Hase T
Reference: 
J Biochem. 2020 May 29:mvaa060

The malaria parasite (Plasmodium sp.) contains a plastid-derived organelle called the apicoplast, which is essential for the growth of the parasite. In this organelle, a redox system comprising plant-type ferredoxin (Fd) and Fd:NADP(H) oxidoreductase (FNR) supplies reducing power for the crucial metabolic pathways. Electron transfer between P. falciparum Fd (PfFd) and FNR (PfFNR) is performed with higher affinity and specificity than those of plant Fd and FNR. We investigated the structural basis for such superior protein-protein interaction by focusing on the Plasumodium-specific regions of PfFd.

NOT Open Access | Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America

February 6, 2019 - 15:39 -- NOT Open Access
Author(s): 
Paula Augusto Taunde, Matheus Viezzer Bianchi, Lívia Perles, Fernando Soares da Silva, Tainã Normanton Guim, Renan Alves Stadler, Marcos Rogério André, David Driemeier & Saulo Petinatti Pavarini
Reference: 
Parasitology Research February 2019, Volume 118, Issue 2, pp 599–606

Avian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium.

Continent: 
Subscribe to RSS - plasmodium sp.