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rapid diagnostic tests

Target Product Profile for a mobile app to read rapid diagnostic tests to strengthen infectious disease surveillance

February 10, 2020 - 16:26 -- Open Access
Author(s): 
Rigveda Kadam, Wallace White, Nicholas Banks, Zachary Katz, Sabine Dittrich, Cassandra Kelly-Cirino
Reference: 
PLoS ONE 15(1):e0228311

The essential role of rapid diagnostic tests (RDTs) in disease control is compromised every time a test is not performed correctly or its result is not reported accurately and promptly. A mobile app that utilizes the camera and connectivity of a common smartphone can fill this role of supporting the test’s proper execution and the automatic transmission of results.

Cost-effectiveness analysis of malaria rapid diagnostic tests: a systematic review

January 14, 2020 - 16:58 -- Open Access
Author(s): 
Ling XX, Jin JJ, Zhu GD, Wang WM, Cao YY, Yang MM, Zhou HY, Cao J, Huang JY
Reference: 
Infect Dis Poverty. 2019 Dec 30; 8(1):104

Rapid diagnostic tests (RDT) can effectively manage malaria cases and reduce excess costs brought by misdiagnosis. However, few studies have evaluated the economic value of this technology. The purpose of this study is to systematically review the economic value of RDT in malaria diagnosis.

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

December 30, 2019 - 15:06 -- Open Access
Author(s): 
Matthew E. Coldiron, Bachir Assao, Rebecca F. Grais, et al.
Reference: 
Malaria Journal 2019 18:443, 26 December 2019

Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high sensitivity. HRP2 tests can remain positive for weeks after treatment, limiting their specificity and usefulness in high-transmission settings. Tests using Plasmodium lactate dehydrogenase (pLDH) have been less widely used but have higher specificity, mostly due to a much shorter time to become negative.

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