Indonesia

Efficacy of a Spatial Repellent for Control of Malaria in Indonesia: A Cluster-Randomized Controlled Trial

Tags:

spatial repellent, malaria, Indonesia, protective efficacy

Author(s):

Syafruddin D, Asih PBS, Achee NL, et al.

Reference:

Am J Trop Med Hyg. 2020 May 18

A cluster-randomized, double-blinded, placebo-controlled trial was conducted to estimate the protective efficacy (PE) of a spatial repellent (SR) against malaria infection in Sumba, Indonesia. Following radical cure in 1,341 children aged ≥ 6 months to ≤ 5 years in 24 clusters, households were given transfluthrin or placebo passive emanators (devices designed to release vaporized chemical).

Molecular surveillance over 14 years confirms reduction of Plasmodium vivax and falciparum transmission after implementation of Artemisinin-based combination therapy in Papua, Indonesia

Tags:

Molecular Surveillance, Plasmodium vivax, falciparum, artemisinin-based combination therapy, Papua, Indonesia

Author(s):

Pava Z, Puspitasari AM, Rumaseb A, Handayuni I, Trianty L, Utami RAS, Tirta YK, Burdam F, Kenangalem E, Wirjanata G, Kho S, Trimarsanto H, Anstey NM, Poespoprodjo JR, Noviyanti R, Price RN, Marfurt J, Auburn S

Reference:

PLoS Negl Trop Dis 14(5): e0008295

Genetic epidemiology can provide important insights into parasite transmission that can inform public health interventions. The current study compared long-term changes in the genetic diversity and structure of co-endemic Plasmodium falciparum and P. vivax populations. The study was conducted in Papua Indonesia, where high-grade chloroquine resistance in P. falciparum and P. vivax led to a universal policy of Artemisinin-based Combination Therapy (ACT) in 2006.

Variation of preventive practices and its association with malaria infection in eastern Indonesia: Findings from community-based survey

Tags:

preventive practices, malaria infection, Indonesia, community-based survey

Author(s):

Ipa M, Widawati M, Laksono AD, Kusrini I, Dhewantara PW

Reference:

PLoS ONE 15(5): e0232909

Geographical variation may likely influence the effectiveness of prevention efforts for malaria across Indonesia, in addition to factors at the individual level, household level, and contextual factors. This study aimed to describe preventive practices at individual and a household levels applied by rural communities in five provinces in eastern Indonesia and its association with the incidence of malaria among adult (≥15 years) populations.

The risk of morbidity and mortality following recurrent malaria in Papua, Indonesia: a retrospective cohort study

Tags:

malaria, Papua, Indonesia, cohort study

Author(s):

Dini S, Douglas NM, Poespoprodjo JR, Kenangalem E, Sugiarto P, Plumb ID, Price RN, Simpson JA

Reference:

BMC Med. 2020 Feb 20;18(1):28

An acute episode of malaria can be followed by multiple recurrent episodes either due to re-infection, recrudescence of a partially treated parasite or, in the case of Plasmodium vivax or P. ovale, relapse from the dormant liver stage of the parasite. The aim of this study was to quantify the impact of recurrent malaria episodes on morbidity and mortality in Papua, Indonesia.

Malaria-related hospitalization during childhood in Papua, Indonesia: A retrospective cohort study

Tags:

malaria, childhood, Papua, Indonesia

Author(s):

Nicholas M. Douglas, Enny Kenangalem, Afdhal Hasanuddin, Nicholas M. Anstey, Paulus Sugiarto, Ric N. Price, Jeanne Rini Poespoprodjo

Reference:

PLoS ONE 15(1):e0228018

In endemic regions, the age distribution of malaria varies according to the infecting Plasmodium species. We aimed to delineate the pattern of malaria-related hospitalization from birth in Timika, Papua–an area co-endemic for P. falciparum and P. vivax

Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia

Tags:

rapid diagnostic test, malaria, pregnancy, Indonesia

Author(s):

Vera T. Unwin, Rukhsana Ahmed, Emily R. Adams, et al.

Reference:

Malaria Journal 2020 19:28, 16 January 2020

The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria. The performance of the Alere™ Ultra-sensitive Malaria Ag Plasmodium falciparum RDT (uRDT) was assessed retrospectively in pregnant women in Indonesia.

Intravenous artesunate plus oral dihydroartemisinin–piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia

Tags:

intravenous artesunate, oral dihydroartemisinin–piperaquine, intravenous quinine, oral quinine, optimum treatment, severe malaria, lesson learnt, field hospital, Timika, Papua, Indonesia

Author(s):

Silvester Alexandro Sikora, Jeanne Rini Poespoprodjo, Enny Kenangalem, Daniel A. Lampah, Paulus Sugiarto, Ida Safitri Laksono, Riris Andono Ahmad and E. Elsa Herdiana Murhandarwati

Reference:

Malaria Journal 2019 18:448, 30 December 2019

Intravenous artesunate and its follow on full course dihydroartemisinin–piperaquine are the standard treatment for severe malaria in Indonesia. The current policy suggests that intravenous and oral quinine could be used when standard therapy is not available. Its pragmatic use of both treatment combinations in a field hospital is evaluated.

What factors do make quality improvement work in primary health care? Experiences of maternal health quality improvement teams in three Puskesmas in Indonesia

Tags:

quality improvement, primary health care, Experiences, maternal health quality, improvement teams, Indonesia

Author(s):

Limato R, Tumbelaka P, Ahmed R, Nasir S, Syafruddin D, Ormel H, Kumar MB, Taegtmeyer M, Kok M

Reference:

PLoS ONE 14(12): e0226804

Indonesia has been shifting from ensuring access to health services towards improving service quality. Accreditation has been used as quality assurance (QA) mechanism, first in hospitals and subsequently in primary health care facilities, including Puskesmas (community health centres). QA provides measures of whether services meet quality targets, but quality improvement (QI) is needed to make change and achieve improvements. QI is a cyclical process with cycles of problem identification, solution testing and observation. We investigated the factors which influenced the process of QI based on experience of maternal health QI teams in three Puskesmas in Cianjur district, West Java province, Indonesia.

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