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Does subsidizing the private for-profit sector benefit the poor? Evidence from national antimalarial subsidies in Nigeria and Uganda

July 28, 2021 - 12:49 -- Open Access
Tougher S, Hanson K, Goodman CA
Health Econ. 2021 Jul 22

Subsidising quality-assured artemisinin combination therapies (QAACTs) for distribution in the for-profit sector is a controversial strategy for improving access. The Affordable Medicines Facility-malaria (AMFm) was the largest initiative of this kind. We assessed the equity of AMFm in two ways using nationally representative household survey data on care seeking for children from Nigeria and Uganda.

Malaria prevalence and long-lasting insecticidal net use in rural western Uganda: results of a cross-sectional survey conducted in an area of highly variable malaria transmission intensity

July 7, 2021 - 14:50 -- Open Access
Claire M. Cote, Varun Goel, Rabbison Muhindo, Emmanuel Baguma, Moses Ntaro, Bonnie E. Shook-Sa, Raquel Reyes, Sarah G. Staedke, Edgar M. Mulogo and Ross M. Boyce
Malaria Journal 2021 20:304, 5 July 2021

Long-lasting insecticidal nets (LLINs) remain a cornerstone of malaria control, but strategies to sustain universal coverage and high rates of use are not well-defined. A more complete understanding of context-specific factors, including transmission intensity and access to health facilities, may inform sub-district distribution approaches and tailored messaging campaigns.

Effectiveness of in-service training plus the collaborative improvement strategy on the quality of routine malaria surveillance data: results of a pilot study in Kayunga District, Uganda

June 30, 2021 - 12:33 -- Open Access
Nelli Westercamp, Sarah G. Staedke, Alexander K. Rowe, et al.
Malaria Journal 2021 20:290, 29 June 2021

Surveillance data are essential for malaria control, but quality is often poor. The aim of the study was to evaluate the effectiveness of the novel combination of training plus an innovative quality improvement method—collaborative improvement (CI)—on the quality of malaria surveillance data in Uganda.

Opening the ‘black box’ of collaborative improvement: a qualitative evaluation of a pilot intervention to improve quality of malaria surveillance data in public health centres in Uganda

June 30, 2021 - 12:31 -- Open Access
Eleanor Hutchinson, Susan Nayiga, Christine Nabirye, Lilian Taaka, Nelli Westercamp, Alexander K. Rowe and Sarah G. Staedke
Malaria Journal 2021 20:289, 29 June 2021

Demand for high-quality surveillance data for malaria, and other diseases, is greater than ever before. In Uganda, the primary source of malaria surveillance data is the Health Management Information System (HMIS). However, HMIS data may be incomplete, inaccurate or delayed. Collaborative improvement (CI) is a quality improvement intervention developed in high-income countries, which has been advocated for low-resource settings. In Kayunga, Uganda, a pilot study of CI was conducted in five public health centres, documenting a positive effect on the quality of HMIS and malaria surveillance data. A qualitative evaluation was conducted concurrently to investigate the mechanisms of effect and unintended consequences of the intervention, aiming to inform future implementation of CI.

Challenges and opportunities for use of long-lasting insecticidal nets to prevent malaria during overnight travel in Uganda: a qualitative study

June 30, 2021 - 12:21 -- Open Access
Deborah Ekusai-Sebatta, Emmanuel Arinaitwe, Arthur Mpimbaza, Joaniter I. Nankabirwa, Chris Drakeley, Philip J. Rosenthal, Sarah G. Staedke and Herbert Muyinda
Malaria Journal 2021 20:283, 26 June 2021

Travel is a well-recognized risk factor for malaria. Within sub-Saharan Africa, travellers from areas of lower to higher transmission intensity are potentially at high risk of malaria. Long-lasting insecticidal nets (LLINs) are the primary tool for prevention of malaria, and their widespread use has contributed to substantial reductions in malaria burden. However, travellers often fail to use LLINs. To further explore the challenges and opportunities of using LLINs, travellers were interviewed in Uganda.

Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study

June 22, 2021 - 15:39 -- Open Access
Andolina C, Rek JC, Bousema T, et al.
Lancet Infect Dis. 2021 Jun 16:S1473-3099(21)00072-4

Symptomatic malaria cases reflect only a small proportion of all Plasmodium spp infections. Many infected individuals are asymptomatic, and persistent asymptomatic Plasmodium falciparum infections are common in endemic settings. We aimed to quantify the contribution of symptomatic and asymptomatic infections to P falciparum transmission in Tororo, Uganda.

Use of the creating opportunities for parent empowerment programme to decrease mental health problems in Ugandan children surviving severe malaria: a randomized controlled trial

June 16, 2021 - 13:13 -- Open Access
Paul Bangirana, Annet Birabwa, Mary Nyakato, Ann J. Nakitende, Maria Kroupina, John M. Ssenkusu, Noeline Nakasujja, Seggane Musisi, Chandy C. John and Richard Idro
Malaria Journal 2021 20:267, 13 June 2021

Severe malaria is associated with long-term mental health problems in Ugandan children. This study investigated the effect of a behavioural intervention for caregivers of children admitted with severe malaria, on the children’s mental health outcomes 6 months after discharge.

Assessment of the accuracy of malaria microscopy in private health facilities in Entebbe Municipality, Uganda: a cross-sectional study

June 9, 2021 - 07:43 -- Open Access
Tobius Mutabazi, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, et al.
Malaria Journal 2021 20:250, 6 June 2021

Although microscopy remains the gold standard for malaria diagnosis, little is known about its accuracy in the private health facilities in Uganda. This study evaluated the accuracy of malaria microscopy, and factors associated with inaccurate smear results at private health facilities in Entebbe Municipality, Uganda.

Genetic diversity and genetic relatedness in Plasmodium falciparum parasite population in individuals with uncomplicated malaria based on microsatellite typing in Eastern and Western regions of Uganda, 2019–2020

June 5, 2021 - 06:24 -- Open Access
Agaba B. Bosco, Karen Anderson, Qin Cheng, et al.
Malaria Journal 2021 20:242, 31 May 2021

Genetic diversity and parasite relatedness are essential parameters for assessing impact of interventions and understanding transmission dynamics of malaria parasites, however data on its status in Plasmodium falciparum populations in Uganda is limited. Microsatellite markers and DNA sequencing were used to determine diversity and molecular characterization of P. falciparum parasite populations in Uganda.

Eave and swarm collections prove effective for biased captures of male Anopheles gambiae mosquitoes in Uganda

June 1, 2021 - 12:37 -- Open Access
Birungi K, Mabuka DP, Balyesima V, Namukwaya A, Chemoges EW, Kiwuwa-Muyingo S, Collins CM, Tripet F, Kayondo JK
Parasit Vectors. 2021 May 26;14(1):281

Traditional malaria vector sampling techniques bias collections towards female mosquitoes. Comprehensive understanding of vector dynamics requires balanced vector sampling of both males and females. Male mosquito sampling is also necessary for population size estimations by male-based mark-release-recapture (MRR) studies and for developing innovations in mosquito control, such as the male-targeted sterile insect technique and other genetic modification approaches. This study evaluated a range of collection methods which show promise in providing a more equal, or even male-biased, sex representation in the sample.


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