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Germany

'Run them dry': a retrospective experience with a restrictive fluid management strategy in severe imported falciparum malaria from a tertiary care university hospital in Berlin, Germany

May 12, 2021 - 09:22 -- Open Access
Author(s): 
Hoffmeister B, Aguilar Valdez AD
Reference: 
Trans R Soc Trop Med Hyg. 2021 May 8;115(5):520-530

Due to the unique pathophysiology with progressive mircocirculatory obstruction and simultaneously increased vascular permeability, overhydration can be rapidly harmful in patients with falciparum malaria. The outcome in all 558 cases hospitalised during 2001-2015 in the Charité University Hospital, Berlin, was favourable, independent of the antimalarial used. Here, the fluid management strategy in the most severely affected subgroup is examined.

Hypertension is associated with an increased risk for severe imported falciparum malaria: a tertiary care hospital based observational study from Berlin, Germany

December 10, 2019 - 08:36 -- Open Access
Author(s): 
Hoffmeister B, Aguilar Valdez AD
Reference: 
Malaria Journal volume 18, 410 (Dec 6, 2019)

Increasing numbers of aging individuals with chronic co-morbidities travel to regions where falciparum malaria is endemic. Non-communicable diseases are now leading risk factors for death in such countries. Thus, the influence of chronic diseases on the outcome of falciparum malaria is an issue of major importance. Aim of the present study was to assess whether non-communicable diseases increase the risk for severe imported falciparum malaria.

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