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Zambia

Impact of mobile health-enhanced supportive supervision and supply chain management on appropriate integrated community case management of malaria, diarrhoea, and pneumonia in children 2-59 months: A cluster randomised trial in Eastern Province, Zambia

June 9, 2020 - 11:39 -- Open Access
Author(s): 
Biemba G, Chiluba B, Yeboah-Antwi K, Silavwe V, Lunze K, Mwale RK, Hamer DH, MacLeod WB
Reference: 
J Glob Health. 2020 Jun;10(1):010425

Despite progress made over the past twenty years, child mortality remains high, with 5.3 million children under five years having died in 2018 globally. Pneumonia, diarrhoea, and malaria remain among the commonest causes of under-five mortality; contributing 15%, 8%, and 5% of global mortality respectively. Recent evidence shows that integrated community case management (iCCM) of pneumonia, diarrhoea, and malaria can reduce under-five mortality. However, despite growing evidence of the effectiveness of iCCM, there are implementation challenges, especially stock out of iCCM commodities and inadequate supportive supervision of community health workers (CHWs). This study aimed to address these two key challenges to successful iCCM implementation by using mobile health (mHealth) technology.

Genetic differentiation and population structure of Anopheles funestus from Uganda and the southern African countries of Malawi, Mozambique, Zambia and Zimbabwe

February 24, 2020 - 13:58 -- Open Access
Author(s): 
Kaddumukasa MA, Wright J, Muleba M, Stevenson JC, Norris DE, Coetzee M
Reference: 
Parasit Vectors. 2020 Feb 18;13(1):87

Anopheles funestus (s.s.) is a primary vector of the malaria parasite Plasmodium falciparum in Africa, a human pathogen that causes almost half a million deaths each year. The population structure of An. funestus was examined in samples from Uganda and the southern African countries of Malawi, Mozambique, Zambia and Zimbabwe.

Knowledge, attitudes and practices assessment of malaria interventions in rural Zambia

February 17, 2020 - 14:36 -- Open Access
Author(s): 
Jumbam DT, Stevenson JC, Matoba J, Grieco JP, Ahern LN, Hamainza B, Sikaala CH, Chanda-Kapata P, Cardol EI, Munachoonga P, Achee NL
Reference: 
BMC Public Health. 2020 Feb 12;20(1):216

Despite rapid upscale of insecticide-treated nets (ITNs) and indoor residual spraying (IRS), malaria remains a major source of morbidity and mortality in Zambia. Uptake and utilization of these and novel interventions are often affected by knowledge, attitudes and practices (KAP) amongst persons living in malaria-endemic areas. The aims of this study were to assess malaria KAP of primary caregivers and explore trends in relation to ITN use, IRS acceptance and mosquito density in two endemic communities in Luangwa and Nyimba districts, Zambia.

The use of spatial and genetic tools to assess Plasmodium falciparum transmission in Lusaka, Zambia between 2011 and 2015

January 20, 2020 - 15:18 -- Open Access
Author(s): 
Daniel J. Bridges, Sandra Chishimba, Mulenga Mwenda, Anna M. Winters, Erik Slawsky, Brenda Mambwe, Conceptor Mulube, Kelly M. Searle, Aves Hakalima, Roy Mwenechanya and David A. Larsen
Reference: 
Malaria Journal 2020 19:20, 15 January 2020

Zambia has set itself the ambitious target of eliminating malaria by 2021. To continue tracking transmission to zero, new interventions, tools and approaches are required.

High Plasmodium falciparum genetic diversity and temporal stability despite control efforts in high transmission settings along the international border between Zambia and the Democratic Republic of the Congo

December 10, 2019 - 08:30 -- Open Access
Author(s): 
Pringle JC, Wesolowski A, Berube S, Kobayashi T, Gebhardt ME, Mulenga M, Chaponda M, Bobanga T, Juliano JJ, Meshnick S, Moss WJ, Carpi G, Norris DE
Reference: 
Malar J. 2019 Dec 4; 18(1):400

While the utility of parasite genotyping for malaria elimination has been extensively documented in low to moderate transmission settings, it has been less well-characterized in holoendemic regions. High malaria burden settings have received renewed attention acknowledging their critical role in malaria elimination. Defining the role for parasite genomics in driving these high burden settings towards elimination will enhance future control programme planning.

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