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sub-Saharan Africa

NOT Open Access | Z Emerging roles for hemostatic dysfunction in malaria pathogenesis

May 22, 2016 - 16:16 -- NOT Open Access
Author(s): 
Jamie M. O’Sullivan, Roger J. S. Preston, Niamh O’Regan, and James S. O’Donnell
Reference: 
Blood, Volume: 127, Issue: 19, Pages: 2281 - 2288

Severe Plasmodium falciparum malaria remains a leading cause of mortality, particularly in sub-Saharan Africa where it accounts for up to 1 million deaths per annum.

Key traveller groups of relevance to spatial malaria transmission: a survey of movement patterns in four sub-Saharan African countries

April 12, 2016 - 16:53 -- Open Access
Tags: 
Author(s): 
John M. Marshall, Mahamoudou Touré, Azra C. Ghani, et al.
Reference: 
Malaria Journal 2016 15:200, 12 April 2016

Women travelling with children were a remarkably consistent traveller group across all four countries surveyed.

Trends in US President’s Malaria Initiative-funded indoor residual spray coverage and insecticide choice in sub-Saharan Africa (2008–2015): urgent need for affordable, long-lasting insecticides

March 10, 2016 - 17:25 -- Open Access
Tags: 
Author(s): 
Richard M. Oxborough
Reference: 
Malaria Journal 2016 15:146, 8 March 2016

This article reports the changing pattern of US President’s Malaria Initiative-funded IRS in sub-Saharan Africa between 2008 and 2015.

Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda

February 18, 2016 - 09:45 -- Open Access
Tags: 
Author(s): 
Pierre De Beaudrap, Eleanor Turyakira, Carolyn Nabasumba, Benon Tumwebaze, Patrice Piola, Yap Boum II and Rose McGready
Reference: 
Malaria Journal 2016 15:92, 16 February 2016

This study shows that despite frequent active screening and prompt treatment of MiP, impaired growth and an increased risk of malaria and non-malaria infections can be observed in the infants.

Country: 

Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim®) in the treatment of uncomplicated malaria at public health facilities in four African countries

January 29, 2016 - 18:46 -- Open Access
Tags: 
Author(s): 
Alexander Adjei, Solomon Narh-Bana, Margaret Gyapong, et al.
Reference: 
Malaria Journal 2016 15:43, 27 January 2016

DHA-PQ was effective and well tolerated in the treatment of uncomplicated malaria and provides an excellent alternative first-line ACT in sub-Saharan Africa.

Missed opportunities to deliver intermittent preventive treatment for malaria to pregnant women 2003–2013: a systematic analysis of 58 household surveys in sub-Saharan Africa

January 2, 2016 - 18:35 -- Open Access
Tags: 
Author(s): 
Kathryn Andrews, Michael Lynch, Erin Eckert, Julie Gutman
Reference: 
Malaria Journal 2015, 14:521 (23 December 2015)

IPTp coverage measured by household surveys is unsatisfactorily low, even many years after policy adoption.

Analysing the nutrition-disease nexus: the case of malaria

December 2, 2015 - 17:25 -- Open Access
Tags: 
Author(s): 
Milinda Lakkam, Lawrence Wein
Reference: 
Malaria Journal 2015, 14:479 (1 December 2015)

Although the results are speculative (e.g., they are based on parameter estimates that do not possess the traditional statistical significance level), the biological plausibility of the modelling assumptions and the high price-sensitivity of demand for bed nets suggest that free bed net distribution targeted to undernutritioned children in areas suffering from both undernutrition and malaria (e.g., sub-Saharan Africa) should be the subject of a randomized trial in a hypoendemic or mesoendemic setting.

Medical Treatment: 

NOT Open Access | Plants as antimalarial agents in Sub-Saharan Africa

November 10, 2015 - 05:17 -- NOT Open Access
Author(s): 
Kazhila C. Chinsembu
Reference: 
Acta Tropica Volume 152, December 2015, Pages 32–48

Although the burden of malaria is decreasing, parasite resistance to current antimalarial drugs and resistance to insecticides by vector mosquitoes threaten the prospects of malaria elimination in endemic areas.

Molecular incidence and clearance of Plasmodium falciparum infection

October 23, 2015 - 06:11 -- Open Access
Author(s): 
Donald Krogstad, Ousmane Koita, Mouctar Diallo, John Gerone, Belco Poudiougou, Mahamadou Diakité, Yéya Touré
Reference: 
Malaria Journal 2015, 14:415 (22 October 2015)

Molecular methods provide information about genetic diversity, the intensity of transmission and spontaneous clearance in the absence of drug treatment that cannot be obtained by microscopy.

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