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sub-Saharan Africa

Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda

February 18, 2016 - 09:45 -- Open Access
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Author(s): 
Pierre De Beaudrap, Eleanor Turyakira, Carolyn Nabasumba, Benon Tumwebaze, Patrice Piola, Yap Boum II and Rose McGready
Reference: 
Malaria Journal 2016 15:92, 16 February 2016

This study shows that despite frequent active screening and prompt treatment of MiP, impaired growth and an increased risk of malaria and non-malaria infections can be observed in the infants.

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Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim®) in the treatment of uncomplicated malaria at public health facilities in four African countries

January 29, 2016 - 18:46 -- Open Access
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Author(s): 
Alexander Adjei, Solomon Narh-Bana, Margaret Gyapong, et al.
Reference: 
Malaria Journal 2016 15:43, 27 January 2016

DHA-PQ was effective and well tolerated in the treatment of uncomplicated malaria and provides an excellent alternative first-line ACT in sub-Saharan Africa.

Missed opportunities to deliver intermittent preventive treatment for malaria to pregnant women 2003–2013: a systematic analysis of 58 household surveys in sub-Saharan Africa

January 2, 2016 - 18:35 -- Open Access
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Author(s): 
Kathryn Andrews, Michael Lynch, Erin Eckert, Julie Gutman
Reference: 
Malaria Journal 2015, 14:521 (23 December 2015)

IPTp coverage measured by household surveys is unsatisfactorily low, even many years after policy adoption.

Analysing the nutrition-disease nexus: the case of malaria

December 2, 2015 - 17:25 -- Open Access
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Author(s): 
Milinda Lakkam, Lawrence Wein
Reference: 
Malaria Journal 2015, 14:479 (1 December 2015)

Although the results are speculative (e.g., they are based on parameter estimates that do not possess the traditional statistical significance level), the biological plausibility of the modelling assumptions and the high price-sensitivity of demand for bed nets suggest that free bed net distribution targeted to undernutritioned children in areas suffering from both undernutrition and malaria (e.g., sub-Saharan Africa) should be the subject of a randomized trial in a hypoendemic or mesoendemic setting.

Medical Treatment: 

NOT Open Access | Plants as antimalarial agents in Sub-Saharan Africa

November 10, 2015 - 05:17 -- NOT Open Access
Author(s): 
Kazhila C. Chinsembu
Reference: 
Acta Tropica Volume 152, December 2015, Pages 32–48

Although the burden of malaria is decreasing, parasite resistance to current antimalarial drugs and resistance to insecticides by vector mosquitoes threaten the prospects of malaria elimination in endemic areas.

Molecular incidence and clearance of Plasmodium falciparum infection

October 23, 2015 - 06:11 -- Open Access
Author(s): 
Donald Krogstad, Ousmane Koita, Mouctar Diallo, John Gerone, Belco Poudiougou, Mahamadou Diakité, Yéya Touré
Reference: 
Malaria Journal 2015, 14:415 (22 October 2015)

Molecular methods provide information about genetic diversity, the intensity of transmission and spontaneous clearance in the absence of drug treatment that cannot be obtained by microscopy.

Associations between urbanicity and malaria at local scales in Uganda

September 30, 2015 - 16:52 -- Open Access
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Author(s): 
Simon Kigozi, Deepa Pindolia, Andrew Tatem, et al.
Reference: 
Malaria Journal 2015, 14:374 (29 September 2015)

Urbanicity has been shown previously to lead to a reduction in malaria transmission at large spatial scales.

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Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria

September 21, 2015 - 16:52 -- Open Access
Author(s): 
Jason P. Mooney, Seung-Joo Lee, Kristen L. Lokken, Minelva R. Nanton, Sean-Paul Nuccio, Stephen J. McSorley, Renée M. Tsolis
Reference: 
PLoS Negl Trop Dis 9(9): e0004027

In immunocompetent individuals, non-typhoidal Salmonella serovars (NTS) are associated with gastroenteritis, however, there is currently an epidemic of NTS bloodstream infections in sub-Saharan Africa.

Malaria impact of large dams in sub-Saharan Africa: maps, estimates and predictions

September 7, 2015 - 08:57 -- Open Access
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Author(s): 
Solomon Kibret, Jonathan Lautze, Matthew McCartney, G. Glenn Wilson, Luxon Nhamo
Reference: 
Malaria Journal 2015, 14:339 (4 September 2015)

In sub-Saharan Africa, dams contribute significantly to malaria risk particularly in areas of unstable transmission.

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