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West Africa

In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine

December 28, 2017 - 16:56 -- Open Access
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Author(s): 
Arnold Donkor Forkuo, Charles Ansah, Kwesi Boadu Mensah, Kofi Annan, Ben Gyan, Anjo Theron, Dalu Mancama and Colin W. Wright
Reference: 
Malaria Journal 2017 16:496, 28 December 2017

The findings of this study shed light on the high gametocytocidal properties of C. sanguinolenta and cryptolepine attributing their potent anti-malarial activity mainly to their effect on both the sexual and asexual stages of the parasite.

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Temporal analysis of IgG antibody responses to Plasmodium falciparum antigens in relation to changing malaria epidemiology in a West African setting

July 11, 2017 - 16:16 -- Open Access
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Author(s): 
Makhtar Niang, Oumy Niass, Aissatou Toure-Balde, et al.
Reference: 
Malaria Journal 2017 16:283, 11 July 2017

The study revealed a substantial contribution of all malaria control interventions to the decrease of IgG antibodies responses to Pfsch07/03 throughout prevention of human-mosquitos contacts, or reduction of parasite biomass.

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Severe malaria in Europe: an 8-year multi-centre observational study

February 8, 2017 - 16:29 -- Open Access
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Author(s): 
Florian Kurth, Michel Develoux, Thomas Zoller, et al.
Reference: 
Malaria Journal 2017 16:57, 31 January 2017

The majority of patients with severe malaria in this study were tourists or migrants acquiring the infection in West Africa.

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Eltahir Group predicts little adverse impact of climate change on malaria in West Africa

December 19, 2016 - 22:08 -- William Jobin

It is important to note a recent report on the predicted impact of climate change on malaria in West Africa, by Teresa K. Yamana, Arne Bomblies and Elfatih A. B. Eltahir. 2016 in the Journal Nature, entitled "Climate change unlikely to increase malaria burden in West Africa." doi:10.1038/nclimate3085

Indoor use of attractive toxic sugar bait (ATSB) to effectively control malaria vectors in Mali, West Africa

August 6, 2015 - 05:51 -- Open Access
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Author(s): 
Whitney A Qualls, Günter C Müller, Sekou F Traore, Mohamed M Traore, Kristopher L Arheart, Seydou Doumbia, Yosef Schlein, Vasiliy D Kravchenko, Rui-De Xue, John C Beier
Reference: 
Malaria Journal 2015, 14:301 (5 August 2015)

The field trial demonstrates that An. gambiae s.l. feed readily from ATSB bait stations situated indoors, leading to a substantial reduction in the proportion of older female mosquitoes.

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High diversity of West African bat malaria parasites and a tight link with rodent Plasmodium taxa

October 29, 2013 - 07:06 -- Open Access
Author(s): 
Juliane Schaer, Susan L. Perkins, Jan Decher, Fabian H. Leendertz, Jakob Fahr, Natalie Weber, and Kai Matuschewski
Reference: 
PNAS October 22, 2013 vol. 110 no. 43 17415-17419
MalariaWorld

As the only volant mammals, bats are captivating for their high taxonomic diversity, for their vital roles in ecosystems—particularly as pollinators and insectivores—and, more recently, for their important roles in the maintenance and transmission of zoonotic viral diseases.

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Feature Article: Evidence for additive and interaction effects of host genotype and infection in malaria

October 17, 2012 - 07:53 -- Kabogo Ndegwa
Author(s): 
Youssef Idaghdour, Jacklyn Quinlan, Jean-Philippe Goulet, Joanne Berghout, Elias Gbeha, Vanessa Bruat, Thibault de Malliard, Jean-Christophe Grenier, Selma Gomez, Philippe Gros, Mohamed Chérif Rahimy, Ambaliou Sanni, and Philip Awadalla
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PNAS October 16, 2012 vol. 109 no. 42 16786-16793

MalariaWorldThe host mechanisms responsible for protection against malaria remain poorly understood, with only a few protective genetic effects mapped in humans.

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Open Access | Host immune response in returning travellers infected with malaria

May 8, 2012 - 14:03 -- Kabogo Ndegwa
Author(s): 
McMullin G, Mackenzie R, Lau R, Khang J, Zhang H, Rajwans N, Liles W, Pillai DR
Reference: 
Malaria Journal 2012, 11:148 (3 May 2012)

MalariaWorldSignificantly higher levels of IL-12 (p40) and lower levels of EGF in CB travellers may serve as useful prognostic markers of disease severity and help guide clinical management upon return.

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Open Access | Mapping the Risk of Anaemia in Preschool-Age Children: The Contribution of Malnutrition, Malaria, and Helminth Infections in West Africa

June 9, 2011 - 07:39 -- Kabogo Ndegwa
Author(s): 
Ricardo J. Soares Magalhães, Archie C. A. Clements
Reference: 
PLoS Med 8(6): e1000438

By mapping the distribution of anaemia risk in preschool children adjusted for malnutrition and parasitic infections, we provide a means to identify the geographical limits of anaemia burden and the contribution that malnutrition and parasites make to anaemia.

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Open Access | Interethnic Differences in Antigen-Presenting Cell Activation and TLR Responses in Malian Children during Plasmodium falciparum Malaria

April 12, 2011 - 08:03 -- Kabogo Ndegwa
Author(s): 
Charles Arama, Pablo Giusti, Stéphanie Boström, Victor Dara, Boubacar Traore, Amagana Dolo, Ogobara Doumbo, Stefania Varani, Marita Troye-Blomberg
Reference: 
PLoS ONE 6(3): e18319

The Fulani ethnic group from West Africa is relatively better protected against Plasmodium falciparum malaria as compared to other sympatric ethnic groups, such as the Dogon.

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