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Evaluation of Antigen Detection Tests, Microscopy, and Polymerase Chain Reaction for Diagnosis of Malaria in Peripheral Blood in Asymptomatic Pregnant Women in Nanoro, Burkina Faso

August 2, 2012 - 12:58 -- Patrick Sampao
Johanna H. Kattenberg, Christian M. Tahita, Inge A. J. Versteeg, Halidou Tinto, Maminata Traoré/Coulibaly, Umberto D'Alessandro, Henk D. F. H. Schallig and Petra F. Mens
Am J Trop Med Hyg 2012 87:251-256

MalariaWorldPregnant women (n = 418) were screened for malaria during routine antenatal care by using two RDTs that detect histidine-rich protein 2 (HRP2) or Plasmodium lactate dehydrogenase, and enzyme-linked immunosorbent assays with antibodies that detect dihydrofolate reductase–thymidylate synthase or heme-detoxification protein, and compared with real-time polymerase chain reaction (RT-PCR) and microscopy for evaluation of their diagnostic accuracy.

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