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Open Access | A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers

March 21, 2011 - 07:29 -- Patrick Sampao
Author(s): 
Roma Chilengi., Rashid Juma., Alexis Nzila., et al.
Reference: 
Malaria Journal 2011, 10:63

Twenty five healthy adult volunteers were recruited and admitted to receive a 5 mg dose of methotrexate/day/5 days. Pharmacokinetics blood sampling was carried out at 2, 4, 6, 12 and 24 hours following each dose.

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