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protein kinases

Targeting Protein Kinases in the Malaria Parasite: Update of an Antimalarial Drug Target

February 22, 2012 - 14:40 -- Patrick Sampao
M. Zhang, Veronica; Chavchich, Marina; C. Waters, Norman
Current Topics in Medicinal Chemistry, Volume 12, Number 5, March 2012 , pp. 456-472(17)

MalariaWorldIn this review, progress on selected protein kinases is described. As the search for novel antimalarials continues, an understanding of the phosphor-regulatory pathways will not only validate protein kinase targets, but also will identify novel chemotypes to thwart malaria drug resistance.

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