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red blood cells

Not Open Access | Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells

July 18, 2012 - 14:41 -- Patrick Sampao
Author(s): 
Olivia C. Finney, Emma Lawrence, Alice P. Gray, Madi Njie, Eleanor M. Riley, Michael Walther
Reference: 
European Journal of Immunology, Volume 42, Issue 7, pages 1767–1777, July 2012

Here, we demonstrate that a freeze/thaw lysate of Plasmodium falciparum schizont extract (PfSE) can induce functionally competent Treg cells from peripheral lymphocytes in a time- and dose-dependent manner without the addition of exogenous costimulatory factors.

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Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells

March 16, 2012 - 13:34 -- Patrick Sampao
Author(s): 
Xuerong Li, Marina Marinkovic, Crystal Russo, C. James McKnight, Theresa L. Coetzer, Athar H. Chishti
Reference: 
Molecular and Biochemical Parasitology, Volume 183, Issue 1, May 2012, Pages 23-31

MalariaWorldTogether, these findings suggest that a recombinant F2i peptide with stabilized structure could provide a protective function at blood stage infection and represents a valuable addition to a multi-subunit vaccine against malaria.

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Flow cytometric enumeration of Plasmodium berghei-infected red blood cells stained with SYBR Green I

February 15, 2012 - 15:08 -- Patrick Sampao
Author(s): 
Voravuth Somsak, Somdet Srichairatanakool, Yongyuth Yuthavong, Sumalee Kamchonwongpaisan, Chairat Uthaipibull
Reference: 
Acta Tropica, Volume 122, Issue 1, April 2012, Pages 113-118

MalariaWorldThis protocol was validated in an antimalarial assay and the result was comparable to that obtained from conventional microscopic counting. The SYBR Green I flow cytometric protocol is thus a rapid and precise tool for high-throughput in vivo antimalarial drug screening.

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Removal of malaria-infected red blood cells using magnetic cell separators: A computational study

February 2, 2012 - 09:45 -- Patrick Sampao
Author(s): 
Jeongho Kim, Mehrdad Massoudi, James F. Antaki, Alberto Gandini
Reference: 
Applied Mathematics and Computation, Volume 218, Issue 12, 15 February 2012, Pages 6841–6850

MalariaWorldIn this paper, we model the malaria-infected RBCs (pRBCs) as paramagnetic particles suspended in a Newtonian fluid.

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