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The Quantity and Quality of African Children's IgG Responses to Merozoite Surface Antigens Reflect Protection against Plasmodium falciparum Malaria

November 10, 2009 - 14:02 -- Ingeborg van Schayk
Courtin D, Oesterholt M, Huismans H, Kusi K, Milet J, et al.
PLoS ONE 4(10): e7590

Our data are consistent with the idea that protection against P. falciparum malaria in children depends on acquisition of a constellation of appropriate, functionally active IgG subclass responses directed to multiple asexual stage antigens.


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