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Factors contributing to anaemia after uncomplicated Plasmodium falciparum malaria in children

January 21, 2010 - 09:05 -- Kabogo Ndegwa
Author(s): 
Akintunde SowunmiCorresponding Grace O. Gbotoshoa, Christian T. Happia and Babasola A. Fateye
Reference: 
Acta Tropica, Volume 113, Issue 2, February 2010, Pages 155-161

The factors contributing to anaemia in falciparum malaria were characterized in 1261 prospectively studied children in an endemic area of southwestern Nigeria.

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Parasitology: Imported malaria in children: incidence and risk factors for severity

January 21, 2010 - 07:52 -- Kabogo Ndegwa
Author(s): 
François Dubosa, Alice Dauriaca, Loubna El Mansoufa, Claude Couroublec, Marie Aurela, Alain Martinota
Reference: 
Diagnostic Microbiology and Infectious Disease, Volume 66, Issue 2, February 2010, Pages 169-174

To assess the incidence of imported malaria in children and to determine the frequency of delayed diagnosis and risk factors for severe malaria, we performed a retrospective multicenter cohort study in the northern region of France and included all children with a positive test for malaria from 2000 to 2006.

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Parasitology: Evaluation of rapid diagnostic tests for malaria case management in Gabon

January 21, 2010 - 07:50 -- Kabogo Ndegwa
Author(s): 
Denise Patricia Mawili-Mboumba, Marielle Karine Bouyou Akoteta, Edgard Brice Ngoungoua and Maryvonne Kombila
Reference: 
Diagnostic Microbiology and Infectious Disease, Volume 66, Issue 2, February 2010, Pages 162-168

These tests should be considered as a good alternative to microscopy, allowing not only an efficient and rapid diagnosis of malaria in primary health facilities but also to aid in promoting changes for antimalarial prescription behavior.

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Open Access | Local scale prediction of Plasmodium falciparum malaria transmission in an endemic region using temperature and rainfall

December 24, 2009 - 14:07 -- Ingeborg van Schayk
Author(s): 
Yazoume´ Ye´ 1*, Moshe Hoshen2, Catherine Kyobutungi1, Vale´ rie R. Louis3 and Rainer Sauerborn4,3
Reference: 
Global Health Action 2009

We develop, fit and validate a non-spatial dynamic model driven by meteorological conditions that can capture seasonal malaria transmission dynamics at the village level in a malaria holoendemic area of north-western Burkina Faso.

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Open Access | Decreasing childhood mortality and increasing proportion of malaria deaths in rural Burkina Faso

December 24, 2009 - 14:00 -- Ingeborg van Schayk
Author(s): 
Heribert Ramroth1*§, Robert P. Ndugwa1§, Olaf Mu¨ ller1, Yazoume Ye´ 2, Ali Sie´ 3, Bocar Kouyate´ 4 and Heiko Becher1
Reference: 
Global Health Action 2009

The aim of this study was to describe temporal trends for malaria and all-cause mortality by combining a series of clinical and intervention studies conducted in Burkina Faso.

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Open Access | Quantitative PCR Evaluation of Cellular Immune Responses in Kenyan Children Vaccinated with a Candidate Malaria Vaccine

December 24, 2009 - 12:55 -- Ingeborg van Schayk
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Author(s): 
Jedidah Mwacharo, Susanna J. Dunachie, Oscar Kai, Adrian V. S. Hill, Philip Bejon, Helen A. Fletcher
Reference: 
PLoS ONE 4(12): e8434

Quantitative PCR is a useful method for evaluating vaccine induced cell mediated immune responses in frozen PBMC from children in a malaria endemic country.

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Open Access | Interactions between Age and ITN Use Determine the Risk of Febrile Malaria in Children

December 24, 2009 - 12:50 -- Ingeborg van Schayk
Author(s): 
Philip Bejon, Edna Ogada, Norbert Peshu, Kevin Marsh
Reference: 
PLoS ONE 4(12): e8321

These data on age interactions with ITN use suggest that larger scale studies on the long term individual outcomes should be undertaken if the policy of targeted ITN use for vulnerable groups is to continue.

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Coagulation Status and Platelet Functions in Children with Severe Falciparum Malaria and their Correlation of Outcome

December 21, 2009 - 12:08 -- Ingeborg van Schayk
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Author(s): 
Rajniti Prasad, B. K. Das, Rahul Pengoria, Om P. Mishra, Jyoti Shukla, and Tej B. Singh
Reference: 
J Trop Pediatr 2009 55: 374-378; doi:10.1093/tropej/fmp028

This study was undertaken to observe the changes in coagulation and platelet profile, and findings were correlated with their outcome.

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High Levels of Plasmodium falciparum Rosetting in All Clinical Forms of Severe Malaria in African Children

December 18, 2009 - 16:23 -- Ingeborg van Schayk
Author(s): 
Ogobara K. Doumbo, Mahamadou A. Thera, Abdoulaye K. Koné, Ahmed Raza, Louisa J. Tempest, Kirsten E. Lyke, Christopher V. Plowe, AND J. Alexandra Rowe
Reference: 
Am J Trop Med Hyg 2009;81 987-993

We investigated the relationship between rosetting and clinical malaria in 209 Malian children enrolled in a case-control study of severe malaria.

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Open Access | Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children

December 8, 2009 - 11:55 -- Ingeborg van Schayk
Author(s): 
Shereen Katrak, Anne Gasasira, Emmanuel Arinaitwe, Abel Kakuru, Humphrey Wanzira, Victor Bigira, Taylor G Sandison, Jaco Homsy, Jordan W Tappero, Moses R Kamya, Grant Dorsey
Reference: 
Malaria Journal 2009, 8:272 (30 November 2009)

Both AL and DP were safe and well tolerated for the treatment of uncomplicated malaria in young HIV-infected and uninfected children.

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