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children

Open Access | Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate

May 13, 2010 - 14:31 -- Kabogo Ndegwa
Author(s): 
Simba DO, Kakoko DC, Warsame M, Premji Z, Gomes MF, Tomson G, Johansson E
Reference: 
Malaria Journal 2010, 9:123 (12 May 2010)

Successful implementation of the rectal artesunate strategy depends upon effective communication regarding referral to clinic.

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Taste-masked quinine pamoate tablets for treatment of children with uncomplicated Plasmodium falciparum malaria

May 12, 2010 - 14:21 -- Patrick Sampao
Author(s): 
E. Kayitare, C. Vervaet, E. Mehuys, P.C. Kayumba, J.D. Ntawukulilyayo, C. Karema, Van Bortel, J.P. Remon
Reference: 
International Journal of Pharmaceutics, Volume 392, Issues 1-2, 15 June 2010, Pages 29-34

This study aimed to develop taste-masked quinine tablets suitable for children and offering dosing flexibility to adjust the quinine dose in function of body weight.

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Open Access | Effect of training on the use of long-lasting insecticide-treated bed nets on the burden of malaria among vulnerable groups, south-west Ethiopia: baseline results of a cluster randomized trial

May 11, 2010 - 07:16 -- Kabogo Ndegwa
Author(s): 
Deribew A, Alemseged F, Birhanu Z, Sena L, Tegegn A, Zeynudin A, Dejene T, Sudhakar M, Abdo N, Tessema F
Reference: 
Malaria Journal 2010, 9:121 (10 May 2010)

The availability and utilization of LLITN was low in the study area. The prevalence of malaria and anaemia was high. Intervention strategies of malaria should focus on high risk population and vulnerable groups.

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‘Like sugar and honey’: The embedded ethics of a larval control project in The Gambia

May 10, 2010 - 12:41 -- Patrick Sampao
Author(s): 
Ann H. Kelly, David Ameh, Silas Majambere, Steve Lindsay, Margaret Pinder
Reference: 
Social Science & Medicine, Volume 70, Issue 12, June 2010, Pages 1912-1919

We found that while participants associated the LCP with the clinical care it provided, they also regarded the collaboration between the nurses and VHWs added additional benefits. Organised around the operational functions of the trial, small-scale collaborations provided the platform from which to build local capacity.

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Open Access | Platelet Factor 4 Regulation of Monocyte KLF4 in Experimental Cerebral Malaria

May 6, 2010 - 12:21 -- Kabogo Ndegwa
Author(s): 
Kalyan Srivastava, David J. Field, Angela Aggrey, Munekazu Yamakuchi, Craig N. Morrell
Reference: 
PLoS ONE 5(5): e10413.

Cerebral malaria continues to be a difficult to treat complication of Plasmodium falciparum infection in children. We have shown that platelets can have major deleterious immune functions in experimental cerebral malaria (ECM).

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Open Access | Bayesian modelling of the effect of climate on malaria in Burundi

April 30, 2010 - 07:42 -- Kabogo Ndegwa
Author(s): 
Nkurunziza H, Gebhardt A, Pilz J
Reference: 
Malaria Journal 2010, 9:114 (29 April 2010)

The results obtained from the proposed models are discussed and it is found that malaria incidence in a given month in Burundi is strongly positively associated with the minimum temperature of the previous month. In contrast, it is found that rainfall and maximum temperature in a given month have a possible negative effect on malaria incidence of the same month.

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Open Access | Short Report: Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children

April 27, 2010 - 15:04 -- Kabogo Ndegwa
Author(s): 
R Idro, A Kakooza-Mwesige, S Balyejjusa, G Mirembe, C Mugasha, J Tugumisirize, J Byarugaba
Reference: 
BMC Research Notes 2010, 3:104

In addition to previously described neurological and cognitive sequelae, severe behaviour problems may follow cerebral malaria in children. The observed differences in patterns of sequelae may be due to different pathogenic mechanisms, brain regions affected or extent of injury. Cerebral malaria may be used as a new model to study the pathogenesis of ADHD.

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Seminar: Malaria in children

April 26, 2010 - 14:02 -- Patrick Sampao
Author(s): 
Jane Crawley, Cindy Chu, George Mtove, François Nosten
Reference: 
The Lancet, Volume 375, Issue 9724, 24 April 2010-30 April 2010, Pages 1468-1481

This Seminar, which is aimed at clinicians who manage children with malaria,especially in resource-poor settings, discusses present knowledge and controversies in relation to the epidemiology, pathophysiology, diagnosis, treatment, and prevention of malaria in children.

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Policy brief on improving access to artemisinin-based combination therapies for malaria in Central African Republic

April 20, 2010 - 15:20 -- Patrick Sampao
Author(s): 
Gérard Gresengueta, Méthode Moyena, Boniface Koffia and Jean Pierre Bangamingoa
Reference: 
International Journal of Technology Assessment in Health Care 26: 242-245 2010

In the Central African Republic (CAR) malaria is a major public health problem and hampers socioeconomic development. It accounts for 40 percent of complaints and 10 percent of deaths in health facilities (15;17).

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Open Access | The relationship between reported fever and Plasmodium falciparum infection in African children

April 20, 2010 - 09:33 -- Kabogo Ndegwa
Author(s): 
Okiro EA, Snow RW
Reference: 
Malaria Journal 2010, 9:99 (19 April 2010)

The potential benefits of diagnosis will depend on the prevalence of infection among children who report fever. The study has demonstrated a predictable relationship between parasite prevalence in the community and risks of infection among febrile children suggesting that current maps of parasite prevalence could be used to guide diagnostic strategies in Africa.

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