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Hydroxyurea for SCA in Africa: no malaria harm

December 19, 2017 - 15:28 -- Open Access
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Author(s): 
Isaac Odame
Reference: 
Blood 14 December 2017, Volume 130, Number 24

The results of the NOHARM trial help address a major barrier to using hydroxyurea treatment in children with SCA in regions where malaria is endemic, thereby moving clinicians a step closer to its wider use across sub-Saharan Africa.

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Seasonal malaria chemoprevention: successes and missed opportunities

November 29, 2017 - 15:32 -- Open Access
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Author(s): 
Matthew E. Coldiron, Lorenz Von Seidlein and Rebecca F. Grais
Reference: 
Malaria Journal 2017 16:481, 28 November 2017

Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season.

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Challenges in implementing uncomplicated malaria treatment in children: a health facility survey in rural Malawi

November 5, 2017 - 18:39 -- Open Access
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Author(s): 
Alinune N. Kabaghe, Mphatso D. Phiri, Kamija S. Phiri and Michèle van Vugt
Reference: 
Malaria Journal 2017 16:419, 18 October 2017

The survey presents an approach for assessing treatment effectiveness, highlighting bottlenecks which coverage indicators are incapable of detecting, and which may reduce quality and effectiveness of malaria treatment.

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Do the venous blood samples replicate malaria parasite densities found in capillary blood? A field study performed in naturally-infected asymptomatic children in Cameroon

August 22, 2017 - 17:55 -- Open Access
Author(s): 
Maurice M. Sandeu, Albert N. Bayibéki, Isabelle Morlais, et al.
Reference: 
Malaria Journal 2017 16:345, 17 August 2017

Plasmodium falciparum malaria parasite densities do not differ between capillary and venous blood in asymptomatic subjects for both gametocyte and trophozoite stages.

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Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels

June 6, 2017 - 15:52 -- Open Access
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Author(s): 
Benjamin F. Arnold, Mark J. van der Laan, Patrick J. Lammie, et al.
Reference: 
PLoS Negl Trop Dis 11(5): e0005616

Age-dependent antibody curves and summary means provided a robust and sensitive measure of changes in transmission, with greatest sensitivity among young children.

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Intermittent preventive treatment for malaria among children in a refugee camp in Northern Uganda: lessons learned

May 25, 2017 - 14:35 -- Open Access
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Author(s): 
Matthew E. Coldiron, Estrella Lasry, Rebecca F. Grais, et al.
Reference: 
Malaria Journal 2017 16:218, 23 May 2017

Northern Uganda hosts a large population of refugees from South Sudan, and malaria is one of the major health problems in the area.

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Comparison of the capacity between public and private health facilities to manage under-five children with febrile illnesses in Uganda

May 9, 2017 - 15:44 -- Open Access
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Author(s): 
Esther Buregyeya, Elizeus Rutebemberwa, Phillip LaRussa, Sham Lal, Sîan E. Clarke, Kristian S. Hansen, Pascal Magnussen and Anthony K. Mbonye
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Malaria Journal 2017 16:183, 2 May 2017

Deficiencies of equipment, supplies and training exist even in public health facilities.

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Continuous determination of blood glucose in children admitted with malaria in a rural hospital in Mozambique

May 9, 2017 - 15:41 -- Open Access
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Author(s): 
Lola Madrid, Antonio Sitoe, Rosauro Varo, Tacilta Nhampossa, Miguel Lanaspa, Abel Nhama, Sozinho Acácio, Isolina Riaño, Aina Casellas and Quique Bassat
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Malaria Journal 2017 16:184, 2 May 2017

Hypoglycaemia beyond admission in children with malaria appears to be much more frequent than what had been previously described.

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Spatial clustering and risk factors of malaria infections in Bata district, Equatorial Guinea

April 18, 2017 - 15:27 -- Open Access
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Author(s): 
Diana Gómez-Barroso, Emely García-Carrasco, Agustín Benito, et al.
Reference: 
Malaria Journal 2017 16:146, 12 April 2017

This study reveals a high prevalence of RDT-based malaria among children in Bata district.

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Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity

April 11, 2017 - 16:02 -- Open Access
Author(s): 
Temitope W. Ademolue, Yaw Aniweh, Kwadwo A. Kusi and Gordon A. Awandare
Reference: 
Malaria Journal 2017 16:145, 11 April 2017

Taken together, the data demonstrate a strong relationship between the prevailing transmission intensity, parasitaemia levels and the magnitude of inflammatory responses induced during clinical malaria.

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