The hypothesis of this study is that this increased susceptibility might be related to infections by parasites expressing the same blood stage allele’s antigens as those to which the infants were exposed in utero.
The aim of this study was to test a theoretical model of children's development using structural equation modeling.
This is the first study to use nationally representative data in exploring inequalities in bed net ownership across countries and its consequences on childhood malaria infection rates.
The study was conducted in two study sites, namely Kersa and Halaba Kulito districts, located in southwest and southern parts of Ethiopia, respectively. Children, aged <= 10 years, who visited the two health centers during the study period, were recruited to the study.
P. vivax associated severe malaria complications observed in this study was lower than those reported from other countries. However, incidence of severe malaria complications in one of the sites, Halaba district, where there is highest treatment failure to first line drug, could have significant impact on national malaria prevention and control activities.
A case--control study was conducted between in four hospitals located in Kinshasa, Democratic Republic of Congo from January 2010 to December 2011. One hundred and twenty nine children were recruited with 43 (cases) and 86 (control).
Despite modest increases in coverage of measures to reduce infection there has been minimal changes in paediatric clinical malaria cases in four hospitals in Malawi.
Development of cerebral malaria (CM), a severe and fatal form of clinical Plasmodium falciparum infection, results from a damaging cascade of vascular, inflammatory, and immunological host responses that leads to brain injury.
We estimated half-life by measuring parasite density every 6 hours until undetectable and evaluated the effects of age, sex, ethnicity, and red blood cell (RBC) polymorphisms on half-life. We quantified the proportion of parasitized RBCs recognized by autologous immunoglobulin G (IgG).
The sensitivity of P. falciparum to SMC drugs should be regularly monitored in areas deploying this intervention.