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Not Open Access | Genetic characterization of Plasmodium falciparum allelic variants infecting mothers at delivery and their children during their first plasmodial infections

September 17, 2013 - 06:43 -- NOT Open Access
Author(s): 
Célia Dechavanne, Charlotte Pierrat, Florence Migot-Nabias, et al.
Reference: 
Infection, Genetics and Evolution, Volume 20, December 2013, Pages 16-25
MalariaWorld

The hypothesis of this study is that this increased susceptibility might be related to infections by parasites expressing the same blood stage allele’s antigens as those to which the infants were exposed in utero.

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NOT Open Access | Developmental effects of micronutrient supplementation and malaria in Zanzibari children

August 7, 2013 - 17:58 -- NOT Open Access
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Author(s): 
Deanna K. Olney, Patricia K. Kariger, Rebecca J. Stoltzfus, Sabra S. Khalfan, Nadra S. Ali, James M. Tielsch, Sunil Sazawal, Robert Black, Lindsay H. Allen, Ernesto Pollitt
Reference: 
Early Human Development, Volume 89, Issue 9, September 2013, Pages 667–674
MalariaWorld

The aim of this study was to test a theoretical model of children's development using structural equation modeling.

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Exploring the impact of targeted distribution of free bed nets on households bed net ownership, socio-economic disparities and childhood malaria infection rates: analysis of national malaria survey data from three sub-Saharan Africa countries

July 18, 2013 - 04:35 -- Open Access
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Author(s): 
Njau JD, Stephenson R, Menon M, Kachur S, McFarland DA
Reference: 
Malaria Journal 2013, 12:245 (15 July 2013)
MalariaWorld

This is the first study to use nationally representative data in exploring inequalities in bed net ownership across countries and its consequences on childhood malaria infection rates.

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Plasmodium vivax associated severe malaria complications among children in some malaria endemic areas of Ethiopia

July 10, 2013 - 18:54 -- Open Access
Author(s): 
Tsige Ketema and Ketema Bacha
Reference: 
BMC Public Health 2013, 13:637
MalariaWorld

The study was conducted in two study sites, namely Kersa and Halaba Kulito districts, located in southwest and southern parts of Ethiopia, respectively. Children, aged <= 10 years, who visited the two health centers during the study period, were recruited to the study.

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Plasmodium vivax associated severe malaria complications among children in some malaria endemic areas of Ethiopia

July 9, 2013 - 15:35 -- Open Access
Author(s): 
Ketema T, Bacha K
Reference: 
BMC Public Health 2013, 13:637 (8 July 2013)
MalariaWorld

P. vivax associated severe malaria complications observed in this study was lower than those reported from other countries. However, incidence of severe malaria complications in one of the sites, Halaba district, where there is highest treatment failure to first line drug, could have significant impact on national malaria prevention and control activities.

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Blackwater fever in Congolese children: a report of clinical, laboratory features and risk factors

June 19, 2013 - 20:40 -- Open Access
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Author(s): 
Bodi JM, Nsibu CN, Longenge RL, Aloni MN, Akilimali PZ, Tshibassu PM, Kayembe PK, Omar AH, Hirayama K, Verhaegen J
Reference: 
Malaria Journal 2013, 12:205 (15 June 2013)
MalariaWorld

A case--control study was conducted between in four hospitals located in Kinshasa, Democratic Republic of Congo from January 2010 to December 2011. One hundred and twenty nine children were recruited with 43 (cases) and 86 (control).

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Childhood Malaria Admission Rates to Four Hospitals in Malawi between 2000 and 2010

May 8, 2013 - 06:34 -- Open Access
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Author(s): 
Emelda A. Okiro, Lawrence N. Kazembe, Caroline W. Kabaria, Jeffrey Ligomeka, Abdisalan M. Noor, Doreen Ali, Robert W. Snow
Reference: 
PLoS ONE 8(4): e62214
MalariaWorld

Despite modest increases in coverage of measures to reduce infection there has been minimal changes in paediatric clinical malaria cases in four hospitals in Malawi.

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NOT Open Access | IFNAR1 Controls Progression to Cerebral Malaria in Children and CD8+ T Cell Brain Pathology in Plasmodium berghei–Infected Mice

May 7, 2013 - 09:38 -- NOT Open Access
Author(s): 
Elizabeth Ann Ball, Maria Rosário Sambo, Madalena Martins, Maria Jesus Trovoada, Carla Benchimol, João Costa, Lígia Antunes Gonçalves, António Coutinho, and Carlos Penha-Gonçalves
Reference: 
The Journal of Immunology May 15, 2013 vol. 190 no. 10 5118-5127
MalariaWorld

Development of cerebral malaria (CM), a severe and fatal form of clinical Plasmodium falciparum infection, results from a damaging cascade of vascular, inflammatory, and immunological host responses that leads to brain injury.

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Plasmodium falciparum Clearance Rates in Response to Artesunate in Malian Children With Malaria: Effect of Acquired Immunity

May 6, 2013 - 17:04 -- Open Access
Author(s): 
Tatiana M. Lopera-Mesa., Saibou Doumbia., Serena Chiang, Amir E., Rick M. Fairhurst., et al
Reference: 
J Infect Dis. (2013) 207 (11):1664-1674.
MalariaWorld

 

We estimated half-life by measuring parasite density every 6 hours until undetectable and evaluated the effects of age, sex, ethnicity, and red blood cell (RBC) polymorphisms on half-life. We quantified the proportion of parasitized RBCs recognized by autologous immunoglobulin G (IgG).

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Prevalence of molecular markers of drug resistance in an area of seasonal malaria chemoprevention in children in Senegal

April 25, 2013 - 07:06 -- Open Access
Author(s): 
Lo AC, Faye B, Gaye O, et al.
Reference: 
Malaria Journal 2013, 12:137 (23 April 2013)
MalariaWorld

The sensitivity of P. falciparum to SMC drugs should be regularly monitored in areas deploying this intervention.

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