Antibodies to merozoite and IE surface antigens increased following infection in early childhood, but neither age at first infection nor number of malaria episodes substantially affected antibody acquisition.
Caregivers should be educated on the importance of promptly seeking care at a health facility where appropriate care can be provided.
In this study, only 30% of children took the recommended first-line treatment.
In sub-Saharan Africa, inherited causes of anemia are common, but data are limited regarding the geographical prevalence and coinheritance of these conditions and their overall contributions to childhood anemia.
Febrile symptoms in children are a leading cause of health-care seeking behaviour worldwide.
Children with febrile encephalopathy are more likely to have malaria than ABM if they have severe anemia.
Associations were complex, with HbAS principally protective against severe anemia, _α/αα against altered consciousness, and negative epistasis between the two polymorphisms.
The results indicate that increased tissue damage and hypercoagulability may play an important role in fatal CM.
Although this study showed clearly that the most prevalent species identified was P. falciparum, the findings demonstrate the existence of non-falciparum malaria, especially P. malariae and P. vivax among children aged ≤ 5 years living both Kinshasa and North Kivu Provinces in DRC.
The parasite Plasmodium falciparum is the main cause of severe malaria (SM). Despite treatment with antimalarial drugs, more than 400,000 deaths are reported every year, mainly in African children.