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Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria

January 2, 2019 - 15:21 -- Open Access
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Author(s): 
Arthur Mpimbaza, Anne Katahoire, Philip J. Rosenthal, Charles Karamagi and Grace Ndeezi
Reference: 
Malaria Journal 2018 17:476, 18 December 2018

Caregivers should be educated on the importance of promptly seeking care at a health facility where appropriate care can be provided.

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Treatments used for malaria in young Ethiopian children: a retrospective study

December 6, 2018 - 16:43 -- Open Access
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Author(s): 
Abyot Endale Gurmu, Teresa Kisi, Habteweld Shibru, Bertrand Graz and Merlin Willcox
Reference: 
Malaria Journal 2018 17:451, 5 December 2018

In this study, only 30% of children took the recommended first-line treatment.

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Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children

November 21, 2018 - 15:24 -- Open Access
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Author(s): 
Patrick T. McGann, Anne M. Williams, Parminder S. Suchdev, et al.
Reference: 
Blood Advances 2018 2:3035-3044

In sub-Saharan Africa, inherited causes of anemia are common, but data are limited regarding the geographical prevalence and coinheritance of these conditions and their overall contributions to childhood anemia.

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Integrated fever management: disease severity markers to triage children with malaria and non-malarial febrile illness

October 16, 2018 - 14:23 -- Open Access
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Author(s): 
Chloe R. McDonald, Andrea Weckman, Melissa Richard-Greenblatt, Aleksandra Leligdowicz and Kevin C. Kain
Reference: 
Malaria Journal 2018 17:353, 10 October 2018

Febrile symptoms in children are a leading cause of health-care seeking behaviour worldwide.

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NOT Open Access | Clinical Predictors of Malaria, Acute Bacterial Meningitis and Treatment Outcomes among Febrile Children Admitted with Altered Mental Status in Northwestern Tanzania

October 9, 2018 - 15:40 -- NOT Open Access
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Author(s): 
Shakilu Jumanne; John Meda; Adolfine Hokororo; Kelvin Leshabari
Reference: 
Journal of Tropical Pediatrics, Volume 64, Issue 5, 1 October 2018, Pages 426–433

Children with febrile encephalopathy are more likely to have malaria than ABM if they have severe anemia.

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Associations between erythrocyte polymorphisms and risks of uncomplicated and severe malaria in Ugandan children: A case control study

October 2, 2018 - 16:31 -- Open Access
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Author(s): 
Arthur Mpimbaza, Andrew Walakira, Grace Ndeezi, Anne Katahoire, Charles Karamagi, Samuel L. Nsobya, Stephen Tukwasibwe, Victor Asua, Philip J. Rosenthal
Reference: 
PLoS ONE 13(9): e0203229

Associations were complex, with HbAS principally protective against severe anemia, _α/αα against altered consciousness, and negative epistasis between the two polymorphisms.

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Proteomic profiling of the plasma of Gambian children with cerebral malaria

September 25, 2018 - 15:15 -- Open Access
Author(s): 
Ehab M. Moussa, Honglei Huang, Climent Casals-Pascual, et al.
Reference: 
Malaria Journal 2018 17:337, 24 September 2018

The results indicate that increased tissue damage and hypercoagulability may play an important role in fatal CM.

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Molecular identification of Plasmodium species in symptomatic children of Democratic Republic of Congo

September 25, 2018 - 15:13 -- Open Access
Author(s): 
Hugo Kavunga-Membo, Gillon Ilombe, Jean Jacques Muyembe, et al.
Reference: 
Malaria Journal 2018 17:334, 20 September 2018

Although this study showed clearly that the most prevalent species identified was P. falciparum, the findings demonstrate the existence of non-falciparum malaria, especially P. malariae and P. vivax among children aged ≤ 5 years living both Kinshasa and North Kivu Provinces in DRC.

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Identification of a Novel Clinical Phenotype of Severe Malaria using a Network-Based Clustering Approach

September 4, 2018 - 16:19 -- Open Access
Author(s): 
Ornella Cominetti, David Smith, Fred Hoffman, Muminatou Jallow, Marie L. Thézénas, Honglei Huang, Dominic Kwiatkowski, Philip K. Maini & Climent Casals-Pascual
Reference: 
Scientific Reports Volume 8, number: 12849 (2018)

The parasite Plasmodium falciparum is the main cause of severe malaria (SM). Despite treatment with antimalarial drugs, more than 400,000 deaths are reported every year, mainly in African children.

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Housing type and risk of malaria among under-five children in Nigeria: evidence from the malaria indicator survey

August 29, 2018 - 15:30 -- Open Access
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Author(s): 
Oyewale M. Morakinyo, Folusho M. Balogun and Adeniyi F. Fagbamigbe
Reference: 
Malaria Journal 2018 17:311, 28 August 2018

Non-improved housing predicted malaria infection among U5s in Nigeria. Improved housing is a promising means to support a more integrated and sustainable approach to malaria prevention.

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