A case–control study was carried out in Kassala and Medani Maternity Hospitals in Sudan to investigate acute-phase proteins [haptoglobin, C-reactive protein (CRP), ferritin and albumin] in three groups of pregnant women (32 in each arm) comprising those with severe Plasmodium falciparum malaria or uncomplicated P. falciparum malaria and healthy controls.
HIV protease inhibitors (PIs) show antimalarial activity in vitro and in animals.
Excessive complement activation is of importance in the pathogenesis of placental malaria by mediating inflammation, coagulation, and endothelial dysfunction.
This study suggests that certain agricultural activities and types of crop production may increase the risk for malaria among women working in small-scale agriculture.
In this analysis, pharmacokinetic modelling suggests that pregnant women have accelerated DHA clearance compared to non-pregnant women receiving orally administered AS.
Plasmodium falciparum has exerted tremendous selective pressure on genes that improve survival in severe malarial infections.
These results suggest that parasites infecting pregnant women persist after delivery and increase the risk of malaria during the postpartum period.
We investigated whether asymptomatic Plasmodium falciparum parasitemia in Beninese women would impair absorption of dietary iron or utilization of circulating iron.
These results help identify the extent of malaria-associated changes women experience during pregnancy.
No abstract available