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pregnant women

Intermittent presumptive treatment in pregnancy with sulfadoxine–pyrimethamine: a counter perspective

June 20, 2015 - 08:27 -- Open Access
Tags: 
Author(s): 
Francois Nosten, Rose McGready
Reference: 
Malaria Journal 2015, 14:248 (20 June 2015)

Malaria continues to cause devastation during pregnancy. Unfortunately, there is still no clear strategy to effectively protect pregnant women and countless mothers living in malaria endemic countries are dying every year.

NOT Open Access | Increasing Prevalence of a Novel Triple-Mutant Dihydropteroate Synthase Genotype in Plasmodium falciparum in Western Kenya

June 17, 2015 - 13:38 -- NOT Open Access
Author(s): 
Naomi W. Lucchi, Sheila Akinyi Okoth, Franklin Komino, Philip Onyona, Ira F. Goldman, Dragan Ljolje, Ya Ping Shi, John W. Barnwell, Venkatachalam Udhayakumar, and Simon Kariuki
Reference: 
Antimicrob. Agents Chemother. July 2015 vol. 59 no. 7 3995-4002

The molecular basis of sulfadoxine-pyrimethamine (SP) resistance lies in a combination of single-nucleotide polymorphisms (SNPs) in two genes coding for Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and P. falciparum dihydropteroate synthase (Pfdhps), targeted by pyrimethamine and sulfadoxine, respectively.

Intervals to Plasmodium falciparum recurrence after anti-malarial treatment in pregnancy: a longitudinal prospective cohort

June 2, 2015 - 06:44 -- Open Access
Author(s): 
Natthapon Laochan, Sophie Zaloumis, Mallika Imwong, Usa Lek-Uthai, Alan Brockman, Kanlaya Sriprawat, Jacher Wiladphaingern, Nicholas White, François Nosten, Rose McGready
Reference: 
Malaria Journal 2015, 14:221 (28 May 2015)

Prolonged time to recrudescence may occur in pregnancy, regardless of anti-malarial treatment.

Medical Treatment: 

Global Call to Action to scale-up coverage of intermittent preventive treatment of malaria in pregnancy: seminar report

May 22, 2015 - 12:53 -- Open Access
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Author(s): 
Koki Agarwal, Pedro Alonso, Jayne Webster, et al.
Reference: 
Malaria Journal 2015, 14:206 (18 May 2015)

In 2014, a global ‘Call to Action’ seminar for the scale-up of intermittent preventive treatment of malaria in pregnancy was held during the 63rd Annual Meeting of the American Society of Tropical Medicine and Hygiene.

The impact of lipid-based nutrient supplementation on anti-malarial antibodies in pregnant women in a randomized controlled trial

May 12, 2015 - 11:04 -- Open Access
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Author(s): 
Upeksha P Chandrasiri, Freya Fowkes, Stephen J Rogerson, et al.
Reference: 
Malaria Journal 2015, 14:193 (10 May 2015)

In the current cohort nutrient supplementation did not affect anti-malarial antibody responses, but poor and undernourished mothers should be a priority group in future trials.

Is there a distinction between malaria treatment and intermittent preventive treatment? Insights from a cross-sectional study of anti-malarial drug use among Ugandan pregnant women

May 4, 2015 - 11:23 -- Open Access
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Author(s): 
Charles O Odongo, Kuteesa R Bisaso, Freddy Kitutu, Celestino Obua, Josaphat Byamugisha
Reference: 
Malaria Journal 2015, 14:189 (3 May 2015)

Use of SP for malaria treatment is common during pregnancy.

Molecular epidemiology and seroprevalence in asymptomatic Plasmodium falciparum infections of Malagasy pregnant women in the highlands

May 4, 2015 - 11:21 -- Open Access
Author(s): 
Oumou Maïga-Ascofaré, Raphael Rakotozandrindrainy, Mirko Girmann, Andreas Hahn, Njary Randriamampionona, Sven Poppert, Jürgen May, Norbert G Schwarz
Reference: 
Malaria Journal 2015, 14:188 (3 May 2015)

Malaria parasites in human Madagascan highland populations trigger immunity but could also be a reservoir for malaria epidemics.

Country: 

Ultrasound findings in pregnant women with uncomplicated vivax malaria in the Brazilian Amazon: a cohort study

April 13, 2015 - 16:29 -- Open Access
Author(s): 
Brock MF, Miranda AE, Bôtto-Menezes C, Leão J, Martinez-Espinosa FE
Reference: 
Malaria Journal 2015, 14 :144 (8 April 2015)

The placental thickness changes were significant but caused no foetal repercussions at birth.

Pregnant women are a reservoir of malaria transmission in Blantyre, Malawi

December 22, 2014 - 13:52 -- Open Access
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Author(s): 
Boudová S, Cohee LM, Kalilani-Phiri L, Thesing PC, Kamiza S, Muehlenbachs A, Taylor TE, Laufer MK
Reference: 
Malaria Journal 2014, 13 :506 (17 December 2014)

Gametocytaemia is present in 5% of pregnant women at their first antenatal visit and associated with placental malaria. SP-IPTp does not alter the risk of gametocytaemia.

Nationwide evaluation of malaria infections, morbidity, mortality, and coverage of malaria control interventions in Madagascar

December 11, 2014 - 05:13 -- Open Access
Tags: 
Author(s): 
Thomas Kesteman, Milijaona Randrianarivelojosia, Chiarella Mattern, Emma Raboanary, Dolorès Pourette, Florian Girond, Vaomalala Raharimanga, Laurence Randrianasolo, Patrice Piola, Christophe Rogier
Reference: 
Malaria Journal 2014, 13:465 (28 November 2014)

This study provides valuable data for the evaluation of effectiveness and factors affecting MCI.

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