This study is the first to document the high prevalence of submicroscopic malaria infections among pregnant women in Haiti and identify social and behavioural risk factors for disease transmission.
The multiplex bead-based immunoassay to detect antibodies against selected 25 VAR2CSA new-peptides and recombinant-domains was successfully implemented.
Genetic variations in CYP3A4 and CYP3A5may influence LF pharmacokinetics and treatment outcome in pregnant women.
By pooling DNA extracts, the allele frequency of mutations in 14 sites could be directly determined on a single deep-sequencing run.
Altogether, data from this study shows that coverage of the 2nd dose of IPTp, as well as ITNs, was low in pregnant women attending ANC services in Mozambique.
The high number of mutants and the presence of quintuple mutants in Burkina Faso confirm concerns about the efficacy of IPTp-SP in the near future.
Women in Cameroon and their antenatal providers missed many opportunities to prevent malaria in pregnancy.
This study showed higher sensitivity of LAMP compared to microscopy and RDT for the detection of malaria in pregnancy.
Interpersonal influence appears to have modest impact on ownership and use of bed nets by pregnant women in an urban area of Ghana.
Antibodies to placental-binding infected erythrocytes may be associated with higher haemoglobin levels in pregnancy, whereas antibodies to other malaria antigens may instead be markers of malaria exposure.