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pregnant women

Open Access | Claims about the Misuse of Insecticide-Treated Mosquito Nets: Are These Evidence-Based?

April 14, 2011 - 12:03 -- Kabogo Ndegwa
Author(s): 
Thomas P. Eisele, Julie Thwing, Joseph Keating
Reference: 
PLoS Med 8(4): e1001019

Nearly all experts agree that insecticide-treated mosquito nets (ITNs) are a lifesaving intervention, supported by strong evidence from carefully conducted trials that show ITNs to be efficacious at preventing all-cause child mortality and malaria morbidity in children and pregnant women.

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Open Access | Malaria associated symptoms in pregnant women followed-up in Benin

April 5, 2011 - 08:17 -- Kabogo Ndegwa
Author(s): 
Huynh B, Fievet N, Gbaguidi G, Borgella S, Guezo Mevo B, Massougbodji A, Deloron P, Cot M
Reference: 
Malaria Journal 2011, 10:72 (31 March 2011)

The majority of pregnant women were symptomless during routine visits when infected with malaria in an endemic stable area.

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Open Access | Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC

March 2, 2011 - 09:01 -- Kabogo Ndegwa
Author(s): 
Onyamboko MA, Meshnick SR, Fleckenstein L, Koch MA, Atibu J, Lokomba V, Douoguih M, Hemmingway-Foday J, Wesche D, Ryder RW, Bose C, Wright LL, Tshefu AK, Capparelli EV
Reference: 
Malaria Journal 2011, 10:49 (28 February 2011)

A single dose of orally administered AS was found to be both effective and without adverse effects in this study of second and third trimester pregnant women in the DRC.

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Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey data

March 2, 2011 - 08:30 -- Patrick Sampao
Author(s): 
Anna Maria van Eijk, Jenny Hill, Victor A Alegana, Viola Kirui, Peter W Gething, Feiko O ter Kuile, Robert W Snow
Reference: 
The Lancet Infectious Diseases, Volume 11, Issue 3, March 2011, Pages 190-207

We extracted data for specific strategies for malaria control in pregnant women from national malariam policies from endemic countries in Africa. We identified the most recent national household cluster-sample surveys recording intermittent preventive treatment with sulfadoxine–pyrimethamine and use of insecticide-treated nets.

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Open Access | Reduced risk for placental malaria in iron deficient women

February 24, 2011 - 12:05 -- Kabogo Ndegwa
Author(s): 
Senga EL, Harper G, Koshy G, Kazembe PN, Brabin BJ
Reference: 
Malaria Journal 2011, 10:47 (23 February 2011)

Women with either acute, or acute and chronic placental malaria were less likely to have iron deficiency than women without placental malaria infection .

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Efficacy of intermittent preventive treatment with sulfadoxine–pyrimethamine on placental parasitemia in pregnant women in midwestern Nigeria

December 14, 2010 - 08:21 -- Patrick Sampao
Author(s): 
Michael E. Aziken, Kenneth K. Akubuo, Etedafe P. Gharoro
Reference: 
International Journal of Gynecology & Obstetrics, Volume 112, Issue 1, January 2011, Pages 30-33

To assess the effect of intermittent preventive treatment with sulfadoxine and pyrimethamine (IPT-SP) on placental parasitemia and maternal and perinatal outcome.

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Effect of Repeated Treatment of Pregnant Women with Sulfadoxine-Pyrimethamine and Azithromycin on Preterm Delivery in Malawi: A Randomized Controlled Trial

December 3, 2010 - 07:55 -- Patrick Sampao
Author(s): 
Mari Luntamo, Teija Kulmala, Bernard Mbewe, Yin Bun Cheung, Kenneth Maleta, AND Per Ashorn
Reference: 
Am J Trop Med Hyg, Dec 2010; 83: 1212 - 1220.

We enrolled 1,320 pregnant women into a randomized, controlled trial in Malawi to study whether preterm delivery and low birth weight (LBW) incidence can be reduced by intermittent preventive treatment of maternal malaria and reproductive tract infections.

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Elevated Levels of Soluble TNF Receptors 1 and 2 Correlate with Plasmodium falciparum Parasitemia in Pregnant Women: Potential Markers for Malaria-Associated Inflammation

November 19, 2010 - 12:35 -- Kabogo Ndegwa
Author(s): 
Audrey Davidson Thévenon, James A. Zhou, Rosette Megnekou, Simon Ako, Rose G. F. Leke, and Diane Wallace Taylor
Reference: 
The Journal of Immunology December 1, 2010 vol. 185 no. 11 7115-7122

Plasmodium falciparum-infected erythrocytes (IEs) sequester in the intervillous space (IVS) of the placenta causing placental malaria (PM), a condition that increases a woman’s chances of having a low-birth-weight baby.

Open Access | Complex Interactions between Soil-Transmitted Helminths and Malaria in Pregnant Women on the Thai-Burmese Border

November 19, 2010 - 12:31 -- Kabogo Ndegwa
Author(s): 
Machteld Boel, Verena I. Carrara, Rose McGready, et al.
Reference: 
PLoS Negl Trop Dis 4(11): e887

A lumbricoides and hookworm appear to have contrary associations with malaria in pregnancy.

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Open Access | Anti-bacterial activity of intermittent preventive treatment of malaria in pregnancy: comparative in vitro study of sulphadoxine-pyrimethamine, mefloquine, and azithromycin

November 3, 2010 - 08:09 -- Kabogo Ndegwa
Author(s): 
Capan M, Mombo-Ngoma G, Makristathis A, Ramharter M
Reference: 
Malaria Journal 2010, 9:303 (29 October 2010)

These data indicate important differences in the spectrum of anti-bacterial activity for the evaluated anti-malarial drugs.

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