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pregnant women

Open Access | Editorial Commentary: The Use of Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine for Preventing Malaria in Pregnant Women

July 18, 2011 - 15:15 -- Patrick Sampao
Author(s): 
Rose Gana Fomban Leke and Diane Wallace Taylor
Reference: 
Clin Infect Dis. (2011) 53 (3): 231-233.

In this issue of the journal, Maiga et al report on a randomized clinical trial performed in Mali, which shows the superiority of 3 over 2 doses of IPTp SP for the prevention of placenta malaria and associated low birth weight infants.

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Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine against Malaria and Anemia in Pregnant Women

July 7, 2011 - 12:26 -- Patrick Sampao
Author(s): 
Nana O. Wilson., Fatou K. Ceesay., Jonathan K. Stiles., et al.
Reference: 
Am J Trop Med Hyg 2011 vol. 85 no. 1 12-21

This study evaluates the effectiveness of IPTp-SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana.

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Prevalence of malaria parasitemia amongst asymptomatic pregnant women attending a Nigerian teaching hospital.

June 24, 2011 - 13:30 -- Patrick Sampao
Author(s): 
Isah AY, Amanabo MA, Ekele BA.
Reference: 
Ann Afr Med. 2011 Apr-Jun;10(2):171-4.

This was a cross-sectional, descriptive study of only well pregnant women recruited consecutively at the time of booking for antenatal care.

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Open Access | Safety, pharmacokinetics and efficacy of artemisinins in pregnancy

June 15, 2011 - 14:42 -- Kabogo Ndegwa
Author(s): 
Veronica Ades
Reference: 
Infectious Disease Reports, Vol 3, No 1 (2011)

Malaria in pregnancy can lead to serious maternal and fetal morbidity and mortality. Access to the most effective antimalarials in pregnancy is essential.

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Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy

June 14, 2011 - 14:26 -- Kabogo Ndegwa
Author(s): 
R. Matthew Chico and Daniel Chandramohan
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 7, pages 774–785, July 2011

The intermittent preventive treatment of malaria in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) has been a key component of the focused antenatal care package for nearly a decade, reducing the burden of low birthweight attributable to malaria in sub-Saharan Africa.

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Open Access | Patterns of anti-malarial drug treatment among pregnant women in Uganda

June 7, 2011 - 07:44 -- Kabogo Ndegwa
Author(s): 
Sangare LR, Weiss NS, Brentlinger PE, Richardson BA, Staedke SG, Kiwuwa MS, Stergachis A
Reference: 
Malaria Journal 2011, 10:152 (6 June 2011)

Self-reported malaria was extremely common in this population and adherence to treatment guidelines for the management of malaria in pregnancy was poor.

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Positive Selection of Plasmodium falciparum Parasites With Multiple var2csa-Type PfEMP1 Genes During the Course of Infection in Pregnant Women

May 19, 2011 - 09:35 -- Patrick Sampao
Author(s): 
Adam F. Sander, Ali Salanti, Thomas Lavstsen, Morten A. Nielsen, Thor G. Theander, Rose G. F. Leke, Yeung Y. Lo, Naveen Bobbili, David E. Arnot and Diane W. Taylor
Reference: 
J Infect Dis. (2011) 203 (11): 1679-1685.

The data suggest that multiplicity of var2csa-type genes enables P. falciparum parasites to persist for a longer period of time during placental infections, probably because of their greater capacity for antigenic variation and evasion of variant-specific immune responses.

Malaria in pregnancy: the difficulties in measuring birthweight

May 10, 2011 - 09:26 -- Kabogo Ndegwa
Author(s): 
MJ Rijken, JA Rijken, AT Papageorghiou, SH Kennedy, GHA Visser, F Nosten, R McGready
Reference: 
BJOG: An International Journal of Obstetrics & Gynaecology, Volume 118, Issue 6, pages 671–678, May 2011

Recommendations for interventions to control malaria in pregnancy are often based on studies using birthweight as the primary endpoint.

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Open Access | Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Cote d'Ivoire

May 5, 2011 - 06:54 -- Kabogo Ndegwa
Author(s): 
Henriette A Vanga-Bosson, Patrick A Coffie, Serge Kanhon, Caroline Sloan, Firmin Kouakou, Serge P Eholie, Moussa Kone, Francois Dabis, Herve Menan, Didier K Ekouevi
Reference: 
Malaria Journal 2011, 10:105 (29 April 2011)

IPT-SP decreases the rate of placental malaria parasitaemia and has a strong dose effect.

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Open Access | Evaluation and pharmacovigilance of projects promoting cultivation and local use of Artemisia annua for malaria

April 20, 2011 - 12:12 -- Kabogo Ndegwa
Author(s): 
Merlin L Willcox, Shelly Burton, Rosalia Oyweka, Rehema Namyalo, Simon Challand, Keith Lindsey
Reference: 
Malaria Journal 2011, 10:84 (11 April 2011)

Local cultivation and preparation of A. annua are feasible where growing conditions are appropriate.

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