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Not Open Access | Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults

August 15, 2012 - 09:51 -- Patrick Sampao
Author(s): 
Pauline Byakika-Kibwika, Mohammed Lamorde, Concepta Merry, et al.
Reference: 
J. Antimicrob. Chemother. (2012) 67 (9): 2213-2221

MalariaWorldWe investigated drug–drug interactions between artemether/lumefantrine and efavirenz or nevirapine.

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Prevalence and clinical features of HIV and malaria co-infection in hospitalized adults in Beira, Mozambique

July 31, 2012 - 13:23 -- Kabogo Ndegwa
Author(s): 
Saracino A, Nacarapa EA, da Costa Massinga EA, Martinelli D, Scacchetti M, de Oliveira C, Antonich A, Galloni D, Ferro JJ, Macome CA
Reference: 
Malaria Journal 2012, 11:241 (26 July 2012)

MalariaWorldMalaria infection was rare in HIV-positive individuals treated with CTX for opportunistic infections, while no independent anti-malarial effect for NNRTIs was noted.

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Open Access | Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia

May 9, 2012 - 10:53 -- Kabogo Ndegwa
Author(s): 
Tjitra E, Hasugian AR, Siswantoro H, Prasetyorini B, Ekowatiningsih R, Yusnita EA, Purnamasari T, Driyah S, Salwati E, Nurhayati N, Yuwarni E, Yanuar L, Labora J, Wijayanto B, Amansyah F, Dedang TA, Purnama A, Trihono T
Reference: 
Malaria Journal 2012, 11:153 (3 May 2012)

MalariaWorldAN and DHP are confirmed very effective, safe and tolerate for treatment of any malaria. Both drugs are promising for multiple first-line therapy policies in Indonesia.

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A spatial analysis of individual- and neighborhood-level determinants of malaria incidence in adults, ontario, Canada

April 25, 2012 - 14:49 -- Patrick Sampao
Author(s): 
Eckhardt R, Berrang-Ford L, Ross NA, Pillai DR, Buckeridge DL.
Reference: 
Emerg Infect Dis. 2012 May;18(5):775-82.

MalariaWorldTo identify geographic and individual determinants of malaria incidence in Ontario, Canada, we conducted a descriptive spatial analysis.

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Open Access | Severe imported malaria in an intensive care unit: a review of 59 cases

April 4, 2012 - 06:47 -- Kabogo Ndegwa
Author(s): 
Santos LC, Abreu CF, Xerinda SM, Tavares M, Lucas R, Sarmento AC
Reference: 
Malaria Journal 2012, 11:96 (29 March 2012)

MalariaWorldSevere malaria cases should be continued monitored in the ICUs.

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Open Access | A high performance liquid chromatographic assay of Mefloquine in saliva after a single oral dose in healthy adult Africans

March 6, 2012 - 06:47 -- Kabogo Ndegwa
Author(s): 
Gbotosho GO, Happi CT, Lawal O, Sijuade A, Sowunmi A, Oduola A
Reference: 
Malaria Journal 2012, 11:59 (27 February 2012)

MalariaWorldDisposition of mefloquine in saliva paralleled that in plasma, making salivary quantification of mefloquine potentially useful in therapeutic drug monitoring.

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Diagnosis and Therapy for Hospitalized Imported Malaria in Adults in Italy

October 26, 2011 - 08:39 -- Kabogo Ndegwa
Author(s): 
Spinello Antinori, Barbara Cigardi, Laura Galimberti, Giovanna Orlando, Luca Schifanella, Laura Milazzo, Anita Viola, Giuseppe Giuliani, Annalisa Ridolfo and Mario Corbellino
Reference: 
Journal of Travel Medicine, Volume 18, Issue 6, pages 379–385, November/December 2011

MalariaWorldIn our study more than two thirds of imported malaria cases were due to P falciparum with an excess of cases diagnosed in immigrants starting from the year 2000.

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Open Access | Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

October 20, 2011 - 08:54 -- Kabogo Ndegwa
Author(s): 
Panda AK, Panda SK, Sahu AN, Tripathy R, Ravindran B, Das BK
Reference: 
Malaria Journal 2011, 10:309 (19 October 2011)

MalariaWorldResults of the current study indicate that blood group 'O' is associated with reduced and 'B' blood group with increased risk of development of severe malaria in Odisha, India.

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Open Access | A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720

October 4, 2011 - 06:38 -- Kabogo Ndegwa
Author(s): 
James S. McCarthy, Joanne Marjason, Robin F. Anders, et al.
Reference: 
PLoS ONE 6(9): e24413

MalariaWorldAs the majority of subjects vaccinated with MSP2-C1 developed an antibody responses to both forms of MSP2, and that these antibodies mediated ADCI provide further support for MSP2 as a malaria vaccine candidate.

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Open Access | A Small Amount of Fat Does Not Affect Piperaquine Exposure in Patients with Malaria

August 18, 2011 - 11:35 -- Kabogo Ndegwa
Author(s): 
Anna Annerberg, Khin Maung Lwin, Niklas Lindegardh, Sakchai Khrutsawadchai, Elizabeth Ashley, Nicholas P. J. Day, Pratap Singhasivanon, Joel Tarning, Nicholas J. White, and François Nosten
Reference: 
Antimicrobial Agents and Chemotherapy, September 2011,p. 3971-3976, Vol. 55, No. 9

Dihydroartemisinin-piperaquine is a new, highly effective, and well-tolerated combination treatment for uncomplicated falciparum malaria.

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