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Minimal Role for the Circumsporozoite Protein in the Induction of Sterile Immunity by Vaccination with Live Rodent Malaria Sporozoites

April 19, 2010 - 14:17 -- Patrick Sampao
Marjorie M., Rita T., et al.
Infection and Immunity, Vol. 78, No. 5 p. 2182-2188, May 2010

Here, we have employed transgenic Plasmodium berghei parasites in which the endogenous CSP was replaced by that of Plasmodium yoelii, another rodent malaria species, to assess the role of CSP in the sterile protection induced by the Spz-plus-CQ protocol.

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