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World Health Organization (WHO)

Adding a single low-dose of primaquine (0.25 mg/kg) to artemether-lumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania: a randomized, single-blinded clinical trial

August 30, 2016 - 15:08 -- Open Access
Author(s): 
Richard Mwaiswelo, Billy Ngasala, Irina Jovel, Berit Aydin-Schmidt, Roland Gosling, Zul Premji, Bruno Mmbando, Anders Björkman and Andreas Mårtensson
Reference: 
Malaria Journal 2016 15:435, 26 August 2016

The new WHO recommendation of adding a single low-dose of PQ to AL did not compromise treatment outcome of uncomplicated P. falciparum malaria in Tanzania.

First evaluation of bendiocarb in experimental huts using different substrates in Madagascar

May 30, 2016 - 16:28 -- Open Access
Tags: 
Author(s): 
Sanjiarizaha Randriamaherijaona, Thiery Nepomichene, Jade Assoukpa, Yoann Madec and Sébastien Boyer
Reference: 
Malaria Journal 2016 15:293, 26 May 2016

Current data suggest variable persistence of bendiocarb according to the type of wall surfaces, highlighting the importance of testing insecticide for IRS in local context before using them in large scale.

Assessing the availability of LLINs for continuous distribution through routine antenatal care and the Expanded Programme on Immunizations in sub-Saharan Africa

May 6, 2016 - 17:59 -- Open Access
Tags: 
Author(s): 
Katherine Theiss-Nyland, Michael Lynch and Jo Lines
Reference: 
Malaria Journal 2016 15:255, 4 May 2016

These continuous LLIN distribution channels appear to be under-utilized, especially EPI-based distribution.

Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study

November 26, 2015 - 05:48 -- Open Access
Author(s): 
Offianan Toure, Stephen Rulisa, Neena Valecha, et al.
Reference: 
Malaria Journal 2015, 14:469 (25 November 2015)

The findings from this study showed that FDC of arterolane maleate and PQP effectively cures P. falciparum malaria and attains acceptable level of cure by day 28 in paediatric patients.

Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of seventh biannual meeting (March 2015)

August 5, 2015 - 12:25 -- Open Access
Tags: 
Author(s): 
WHO Malaria Policy Advisory Committee and Secretariat
Reference: 
Malaria Journal 2015, 14:295 (5 August 2015)

The Malaria Policy Advisory Committee to the World Health Organization held its seventh meeting in Geneva, Switzerland from 5 to 7 March 2015.

Malaria continues to select for sickle cell trait in Central Africa

June 4, 2015 - 08:27 -- Open Access
Tags: 
Author(s): 
Eric Elguero, Lucrèce M. Délicat-Loembet, Franck Prugnolle, et al.
Reference: 
PNAS June 2, 2015 vol. 112 no. 22 7051-7054

Sickle cell disease (SCD) is a genetic disorder that poses a serious health threat in tropical Africa, which the World Health Organization has declared a public health priority.

Continent: 

Re-imagining the control of malaria in tropical Africa during the early years of the World Health Organization

April 24, 2015 - 09:13 -- Open Access
Tags: 
Author(s): 
Socrates Litsios
Reference: 
Malaria Journal 2015, 14:178 (24 April 2015)

This paper grew out of a meeting organized in October 2014 in London on ‘Re-imagining malaria’.

Quality assurance of malaria rapid diagnostic tests used for routine patient care in rural Tanzania: microscopy versus real-time polymerase chain reaction

March 2, 2015 - 18:37 -- Open Access
Tags: 
Author(s): 
Irene M Masanja, Meredith L McMorrow, Mussa B Maganga, Debora Sumari, Venkatachalam Udhayakumar, Peter D McElroy, S Kachur, Naomi W Lucchi
Reference: 
Malaria Journal 2015, 14:85 (19 February 2015)

Overall there was limited agreement among the three diagnostic approaches and neither microscopy nor qPCR appear to be good QA options for RDTs under field conditions.

Country: 

NOT Open Access | Improving the Role and Contribution of Pharmacokinetic Analyses in Antimalarial Drug Clinical Trials

September 19, 2014 - 14:58 -- NOT Open Access
Author(s): 
Katherine Kay, Eva Maria Hodel, and Ian M. Hastings
Reference: 
Antimicrob. Agents Chemother. October 2014 vol. 58 no. 10 5643-5649

It is now World Health Organization (WHO) policy that drug concentrations on day 7 be measured as part of routine assessment in antimalarial drug efficacy trials.

World Health Day (7 April) about vector-borne diseases

February 24, 2014 - 19:50 -- Bart G.J. Knols

This year World Health Day has its focus on vector-borne diseases, including malaria. The World Health Organization has set specific goals for this day, and is asking the international community working on malaria and other vectors to pay special attention towards protection from vector-borne diseases.

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