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World Health Organization

Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study

July 27, 2016 - 07:17 -- Open Access
Author(s): 
Eugenie Poirot, Adam Soble, Roland Gosling, et al.
Reference: 
Malaria Journal 2016 15:384, 22 July 2016

Improved pharmacovigilance to monitor and promote the safety of the WHO recommendation is needed.

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Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial

July 2, 2016 - 16:15 -- Open Access
Author(s): 
Joshua Kimani, Kamija Phiri, Steve Kamiza, Stephan Duparc, Ayman Ayoub, Ricardo Rojo, Jeffery Robbins, Russell Orrico, Pol Vandenbroucke
Reference: 
PLoS ONE 11(6): e0157045

IPTp-AZCQ was not superior to IPTp-SP in this study and alternatives for IPTp-SP remain to be identified.

Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries

March 2, 2016 - 17:40 -- Open Access
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Author(s): 
Katherine Theiss-Nyland, Waqo Ejersa, Jo Lines, et al.
Reference: 
Malaria Journal 2016 15:131, 1 March 2016

In these countries, stock-outs were the most important single obstacle to the smooth operations of continuous LLIN distribution.

Simultaneous quantification of artesunate and mefloquine in fixed-dose combination tablets by multivariate calibration with middle infrared spectroscopy and partial least squares regression

February 26, 2016 - 17:14 -- Open Access
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Author(s): 
Breno Maurício Marson, Raquel de Oliveira Vilhena, Camilla Regina de Souza Madeira, Flávia Lada Degaut Pontes, Mário Sérgio Piantavini and Roberto Pontarolo
Reference: 
Malaria Journal 2016 15:109, 24 February 2016

MIR-PLS was found to be suitable for the quality control of these drugs.

Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of eighth biannual meeting (September 2015)

February 26, 2016 - 17:12 -- Open Access
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Author(s): 
WHO Malaria Policy Advisory Committee and Secretariat
Reference: 
Malaria Journal 2016 15:117, 24 February 2016

The Malaria Policy Advisory Committee (MPAC) to the World Health Organization held its eighth meeting in Geneva, Switzerland from 16 to 18 September 2015.

Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis

May 18, 2015 - 12:51 -- Open Access
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Author(s): 
Ross M Boyce, Anthony Muiru, Raquel Reyes, Moses Ntaro, Edgar Mulogo, Michael Matte, Mark J Siedner
Reference: 
Malaria Journal 2015, 14:203 (15 May 2015)

This study is one of the few to demonstrate significant improvement in clinical outcomes and process measures following the introduction of RDTs for the diagnosis of malaria at a rural health facility in Uganda.

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Biodiversity Can Help Prevent Malaria Outbreaks in Tropical Forests

March 27, 2013 - 06:51 -- Open Access
Author(s): 
Gabriel Zorello Laporta, Paulo Inácio Knegt Lopez de Prado, Roberto André Kraenkel, Renato Mendes Coutinho, Maria Anice Mureb Sallum
Reference: 
PLoS Negl Trop Dis 7(3): e2139
MalariaWorld

To achieve biological conservation and to eliminate Plasmodium parasites in human populations, the World Health Organization Malaria Eradication Research Agenda should take biodiversity issues into consideration.

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region

January 13, 2013 - 13:48 -- Open Access
Author(s): 
Abdulla S, Salim N, Tanner M, et al.
Reference: 
Malaria Journal 2013, 12:11 (8 January 2013)
MalariaWorld

Safety, immunogenicity and efficacy of the RTS,S/AS02D vaccine candidate when integrated into a standard EPI schedule for infants have been reported over a nine-month surveillance period. This paper describes results following 20 months of follow up.

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Opinion: Health Systems Perspectives - Infectious Diseases of Poverty

November 25, 2012 - 14:24 -- Open Access
Author(s): 
Dale Huntington
Reference: 
Infectious Diseases of Poverty 2012, 1:12
MalariaWorld

This new journal reminds us of the essential characteristic of poverty as a violent abuse of human rights. The context of poverty ? its social, political and economic dimensions ? remain in the reader?s mind as evidence is provided on technical solutions to managing the infectious diseases that afflict poor populations world-wide

A cost-effectiveness analysis of provider and community interventions to improve the treatment of uncomplicated malaria in Nigeria: study protocol for a randomized controlled trial

June 21, 2012 - 10:54 -- Patrick Sampao
Author(s): 
Wiseman Virginia, Ezeoke Ogochukwu, Nwala Emmanuel, Mangham Lindsay J, Cundill Bonnie, Enemuo Jane, Uchegbu Eloka, Uzochukwu Benjamin and Onwujekwe Obinna
Reference: 
Trials 2012, 13:81

MalariaWorldThe primary outcome is the proportion of patients attending facilities that report a fever or suspected malaria and receive treatment according to malaria guidelines.

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