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Open Access | Review: Automated haematology analysis to diagnose malaria

December 2, 2010 - 06:32 -- Kabogo Ndegwa
Author(s): 
Campuzano-Zuluaga G, Hanscheid T, Grobusch MP
Reference: 
Malaria Journal 2010, 9:346 (30 November 2010)

For more than a decade, flow cytometry-based automated haematology analysers have been studied for malaria diagnosis.

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Open Access | Complex Interactions between Soil-Transmitted Helminths and Malaria in Pregnant Women on the Thai-Burmese Border

November 19, 2010 - 12:31 -- Kabogo Ndegwa
Author(s): 
Machteld Boel, Verena I. Carrara, Rose McGready, et al.
Reference: 
PLoS Negl Trop Dis 4(11): e887

A lumbricoides and hookworm appear to have contrary associations with malaria in pregnancy.

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Open Access | Editorial: Malaria therapy: where do we stand, what next?

November 18, 2010 - 12:28 -- Patrick Sampao
Author(s): 
Martin Peter Grobusch & Michèle van Vugt
Reference: 
Future Microbiology, October 2010, Vol. 5, No. 10, Pages 1447-1449

The guidelines emphasize appropriate case management, such as to treat for malaria only after diagnosis by means of rapid diagnostic ‘dipstick’ testing (RDT) in places where reliable light microscopy cannot be performed; and to base treatment on clinical suspicion only if parasitological diagnosis is inaccessible.

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Open Access | Entomologic and molecular investigation into Plasmodium vivax transmission in Singapore, 2009

November 3, 2010 - 08:20 -- Kabogo Ndegwa
Author(s): 
Ng L, Lee K, Tan C, Ooi P, Lam-Phua S, Lin R, Pang S, Lai Y, Solhan S, Chan P, Wong K, Ho S, Vythilingam I
Reference: 
Malaria Journal 2010, 9:305 (29 October 2010)

Investigation of P. vivax cases from the three cluster areas confirmed the occurrence of local transmission in two areas.

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Open Access | Elevated Cell-Specific Microparticles Are a Biological Marker for Cerebral Dysfunctions in Human Severe Malaria

October 22, 2010 - 14:20 -- Kabogo Ndegwa
Author(s): 
Joël Bertrand Pankoui Mfonkeu, Inocent Gouado, Honoré Fotso Kuaté, Odile Zambou, Paul Henri Amvam Zollo, Georges Emile Raymond Grau, Valéry Combes
Reference: 
PLoS ONE 5(10): e13415

Cerebral malaria (CM) and severe anemia (SA) are the most severe complications of Plasmodium falciparum infections.

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Open Access | Population screening for glucose-6-phosphate dehydrogenase deficiencies in Isabel Province, Solomon Islands, using a modified enzyme assay on filter paper dried bloodspots

August 6, 2010 - 13:54 -- Kabogo Ndegwa
Author(s): 
Kuwahata M, Wijesinghe R, Ho M, Pelecanos A, Bobogare A, Landry L, Bugora H, Vallely A, McCarthy J
Reference: 
Malaria Journal 2010, 9:223 (5 August 2010)

The assay enabled simple and quick semi-quantitative population screening in a malaria-endemic region. The study indicated a high prevalence of G6PD deficiency in Isabel Province and highlights the critical need to consider G6PD deficiency in the context of P. vivax malaria elimination strategies in Solomon Islands, particularly in light of the potential role of primaquine mass drug administration.

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Open Access | Essay: Assessing Strategy and Equity in the Elimination of Malaria

August 5, 2010 - 11:49 -- Kabogo Ndegwa
Author(s): 
Naman K. Shah
Reference: 
PLoS Med 7(8): e1000312

After the 2007 Bill & Melinda Gates Foundation meeting at which malaria eradication was declared back on the table [1], the charity was joined in its call by the World Health Organization (WHO) director general, the United States National Institutes of Health, and the Clinton Foundation, among others.

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Open Access | High Level of Pyrethroid Resistance in an Anopheles funestus Population of the Chokwe District in Mozambique

June 11, 2010 - 09:12 -- Kabogo Ndegwa
Author(s): 
Nelson Cuamba, John C. Morgan, Helen Irving, Andrew Steven, Charles S. Wondji
Reference: 
PLoS ONE 5(6): e11010.

The high level of pyrethroid resistance in this population despite the cessation of pyrethroid use for IRS in 1999 is a serious concern for resistance management strategies such as rotational use of insecticides. As DDT has now been re-introduced for IRS, susceptibility to DDT needs to be closely monitored to prevent the appearance and spread of resistance to this insecticide.

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Advances in the treatment of malaria

May 10, 2010 - 09:11 -- Kabogo Ndegwa
Author(s): 
D Lalloo, DJ Bell
Reference: 
Br J Hosp Med (Lond). 2010 May;71(5):246-7

The World Health Organization campaign for malaria eradication was abandoned in 1969 in favour of a strategy of malaria control after it became clear that worldwide eradication could not be achieved using the tools available at that time.

 

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Update: Monitoring antimalarial resistance: launching a cooperative effort

April 28, 2010 - 15:43 -- Patrick Sampao
Author(s): 
Carol Hopkins Sibley, Philippe J. Guerin, Pascal Ringwald
Reference: 
Trends in Parasitology, Volume 26, Issue 5, May 2010, Pages 221-224

A collaborative effort between the Global Malaria Program of the World Health Organization (WHO) and the WorldWide Antimalarial Resistance Network (WWARN) has recently been launched.

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