Encouraged by the early success of using dichloro-diphenyl-trichloroethane (DDT) against malaria, the World Health Organization (WHO) embarked on the Global Malaria Eradication Program (GMEP) in 1955.
The choice of anti-malarial drug should be an evidence-based decision that considers the profile of the individual traveller and the risk of malaria.
For more than a decade, flow cytometry-based automated haematology analysers have been studied for malaria diagnosis.
A lumbricoides and hookworm appear to have contrary associations with malaria in pregnancy.
The guidelines emphasize appropriate case management, such as to treat for malaria only after diagnosis by means of rapid diagnostic ‘dipstick’ testing (RDT) in places where reliable light microscopy cannot be performed; and to base treatment on clinical suspicion only if parasitological diagnosis is inaccessible.
Investigation of P. vivax cases from the three cluster areas confirmed the occurrence of local transmission in two areas.
Cerebral malaria (CM) and severe anemia (SA) are the most severe complications of Plasmodium falciparum infections.
The assay enabled simple and quick semi-quantitative population screening in a malaria-endemic region. The study indicated a high prevalence of G6PD deficiency in Isabel Province and highlights the critical need to consider G6PD deficiency in the context of P. vivax malaria elimination strategies in Solomon Islands, particularly in light of the potential role of primaquine mass drug administration.
After the 2007 Bill & Melinda Gates Foundation meeting at which malaria eradication was declared back on the table , the charity was joined in its call by the World Health Organization (WHO) director general, the United States National Institutes of Health, and the Clinton Foundation, among others.
The high level of pyrethroid resistance in this population despite the cessation of pyrethroid use for IRS in 1999 is a serious concern for resistance management strategies such as rotational use of insecticides. As DDT has now been re-introduced for IRS, susceptibility to DDT needs to be closely monitored to prevent the appearance and spread of resistance to this insecticide.