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Open Access | Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro

July 12, 2011 - 07:53 -- Kabogo Ndegwa
Author(s): 
Kwansa-Bentum B, Ayi I, Suzuki T, Otchere J, Kumagai T, Anyan WK, Osei JH, Asahi H, Ofori MF, Akao N, Wilson MD, Boakye DA, Ohta N
Reference: 
Malaria Journal 2011, 10:187 (11 July 2011)

The pfATPase6 gene is highly polymorphic with D639G appearing to be fixed in Ghanaian isolates.

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Open Access | Comparative study of the efficacy and tolerability of dihydroartemisinin - piperaquine - trimethoprim versus artemether - lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal

July 12, 2011 - 07:41 -- Kabogo Ndegwa
Author(s): 
Menan H, Faye O, Same-Ekobo A, Oga AS, Faye B, Kiki-Barro CP, Kuete T, N'diaye J, Vicky A, Tine R, Yavo W, Kane D, Kassi KF, Kone M
Reference: 
Malaria Journal 2011, 10:185 (8 July 2011)

The overall efficacy and tolerability of DPT are similar to those of AL.

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Open Access | Status of Legislation and Regulatory Control of Public Health Pesticides in Countries Endemic with or at Risk of Major Vector-borne Diseases

July 12, 2011 - 07:34 -- Kabogo Ndegwa
Author(s): 
Graham Matthews, Morteza Zaim, Rajpal Singh Yadav, Agnes Soares, Jeffrey Hii, Birkinesh Ameneshewa, Abraham Mnzava, Aditya Prashad Dash, Mikhail Ejov, Soo Hian Tan, Henk van den Berg
Reference: 
Environ Health Perspect, ehp.1103637

Critical deficiencies are evident in the legislative and regulatory framework for public health pesticides across Regions, posing risks to human health and the environment.

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Open Access | "Test and treat" or presumptive treatment for malaria in high transmission situations? A reflection on the latest WHO guidelines

May 25, 2011 - 08:45 -- Kabogo Ndegwa
Author(s): 
Graz B, Willcox M, Szeless T, Rougemont A
Reference: 
Malaria Journal 2011, 10:136 (20 May 2011)

Recent WHO guidelines recommend a universal "test and treat" strategy for malaria, mainly by use of rapid diagnostic test (RDT) in all areas.

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Open Access | Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Cote d'Ivoire

May 5, 2011 - 06:54 -- Kabogo Ndegwa
Author(s): 
Henriette A Vanga-Bosson, Patrick A Coffie, Serge Kanhon, Caroline Sloan, Firmin Kouakou, Serge P Eholie, Moussa Kone, Francois Dabis, Herve Menan, Didier K Ekouevi
Reference: 
Malaria Journal 2011, 10:105 (29 April 2011)

IPT-SP decreases the rate of placental malaria parasitaemia and has a strong dose effect.

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Open Access | Grand Rounds: The Opportunity for and Challenges to Malaria Eradication

April 26, 2011 - 14:50 -- Patrick Sampao
Author(s): 
KE Mace, PhD,* MF Lynch, MD, JR MacArthur, MD, SP Kachur, MD, L Slutsker, MD
Reference: 
Morbidity and Mortality Weekly Report (MMWR), April 22, 2011 / 60(15);476-480

These reports are based on grand rounds presentations at CDC on high-profile issues in public health science, practice, and policy.

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Open Access | New hope in the fight against malaria?

March 29, 2011 - 06:55 -- Kabogo Ndegwa
Author(s): 
Tiago Rodrigues, Rui Moreira and Francisca Lopes
Reference: 
Future Medicinal Chemistry, January 2011, Vol. 3, No. 1, Pages 1-3

Malaria is still one of the major vector-borne infectious diseases in the world.

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Open Access | District level external quality assurance (EQA) of malaria microscopy in Pakistan: pilot implementation and feasibility

February 23, 2011 - 09:48 -- Kabogo Ndegwa
Author(s): 
Khan M
Reference: 
Malaria Journal 2011, 10:45 (17 February 2011)

A district-based EQA, based on lot quality assurance methods was implemented, using context-specific operational guidelines, tools and training modules, and other inputs from the malaria control programme and partners.

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Open Access | Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi

February 15, 2011 - 09:02 -- Kabogo Ndegwa
Author(s): 
Amuasi JH, Diap G, Blay-Nguah S, Boakye I, Karikari PE, Dismas B, Karenzo J, Nsabiyumva L, Louie KS, Kiechel J
Reference: 
Malaria Journal 2011, 10:34 (10 February 2011)

AS-AQ was widely available and affordable in the public and NGO markets of hard-to-reach post-conflict communities in Burundi.

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Open Access | Some Lessons for the Future from the Global Malaria Eradication Programme (1955–1969)

January 27, 2011 - 10:05 -- Kabogo Ndegwa
Author(s): 
José A. Nájera, Matiana González-Silva, Pedro L. Alonso
Reference: 
PLoS Med 8(1): e1000412

Encouraged by the early success of using dichloro-diphenyl-trichloroethane (DDT) against malaria, the World Health Organization (WHO) embarked on the Global Malaria Eradication Program (GMEP) in 1955.

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