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A significant association between deltamethrin resistance, Plasmodium falciparum infection and the Vgsc-1014S resistance mutation in Anopheles gambiae highlights the epidemiological importance of resistance markers

May 25, 2016 - 17:43 -- Open Access
Author(s): 
Bilali Kabula, Patrick Tungu, Emily J. Rippon, Keith Steen, William Kisinza, Stephen Magesa, Franklin Mosha and Martin James Donnelly
Reference: 
Malaria Journal 2016 15:289, 23 May 2016

One marker, Vgsc-1014S, was associated with insecticide resistance and P. falciparum infection in wild-caught mixed aged populations of A. gambiae s.s. thereby showing how resistance may directly impact transmission.

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Does insecticide resistance contribute to heterogeneities in malaria transmission in The Gambia?

March 16, 2016 - 17:43 -- Open Access
Author(s): 
Kevin Ochieng’ Opondo, David Weetman, Musa Jawara, Mathurin Diatta, Amfaal Fofana, Florence Crombe, Julia Mwesigwa, Umberto D’Alessandro and Martin James Donnelly
Reference: 
Malaria Journal 2016 15:166, 15 March 2016

Whilst causality of relationships requires further investigation, variation in vector species and insecticide resistance in The Gambia is associated with malaria endemicity; with a notably higher prevalence of infection and insecticide resistance in the east of the country.

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Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands

February 9, 2016 - 17:01 -- Open Access
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Author(s): 
Bryson A. Ndenga, Nicholas L. Mulaya, Sandra K. Musaki, Joan N. Shiroko, Stefan Dongus and Ulrike Fillinger
Reference: 
Malaria Journal 2016 15:76, 9 February 2016

An unusually high frequency of animal and mixed human-animal blood meals in the major malaria vector An. gambiae s.s. was revealed in the western Kenya highlands where bed net coverage is above the WHO target.

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Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

February 8, 2016 - 16:45 -- Open Access
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Author(s): 
Peter G. Kremsner, Akim A. Adegnika, Sanjeev Krishna, et al.
Reference: 
PLoS Med 13(1): e1001938

A simplified three-dose i.m. regimen for severe malaria in African children is non-inferior to the more complex WHO-recommended regimen.

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Field evaluation of the 22 rapid diagnostic tests for community management of malaria with artemisinin combination therapy in Cameroon

January 26, 2016 - 19:27 -- Open Access
Author(s): 
Innocent M. Ali, Jude D. Bigoga, Rose G. F. Leke, et al.
Reference: 
Malaria Journal 2016 15:31, 20 January 2016

Overall, 94.2 % (21/22) of RDTs tested had accuracy within the range recommended by the WHO, while one performed poorly, below acceptable levels.

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Improving the quality of paediatric malaria diagnosis and treatment by rural providers in Myanmar: an evaluation of a training and support intervention

October 14, 2015 - 06:44 -- Open Access
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Author(s): 
Tin Aung, Kim Longfield, Nyo Aye, Aung San, Thea Sutton, Dominic Montagu, PHSi/UCSF Global Health Group
Reference: 
Malaria Journal 2015, 14:397 (9 October 2015)

The SPH training programme was able to improve the quality of paediatric malaria care significantly, and to maintain that improvement over time.

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NOT Open Access | Trends in malaria case management following changes in the treatment policy to artemisinin combination therapy at the Mbakong Health Centre, Cameroon 2006–2012: A retrospective study

October 5, 2015 - 16:46 -- NOT Open Access
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Author(s): 
Ignatius C Ndong, Mari van Reenen, Daniel A Boakye, Wilfred F Mbacham, Anne F Grobler
Reference: 
Acta Tropica, Volume 150, October 2015, Pages 100–106

National malaria treatment policies are devised to guide health professionals and to facilitate diagnosis and case management.

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A new class of insecticide for malaria vector control: evaluation of mosquito nets treated singly with indoxacarb (oxadiazine) or with a pyrethroid mixture against Anopheles gambiae and Culex quinquefasciatus

September 22, 2015 - 17:47 -- Open Access
Author(s): 
Richard Oxborough, Raphael N’Guessan, Jovin Kitau, Patrick Tungu, David Malone, Franklin Mosha, Mark Rowland
Reference: 
Malaria Journal 2015, 14:353 (17 September 2015)

New insecticides with different modes of action to those currently used in mosquito vector control are urgently needed.

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NOT Open Access | Availability and price of malaria rapid diagnostic tests in the public and private health sectors in 2011: results from 10 nationally representative cross-sectional retail surveys

May 6, 2015 - 14:04 -- NOT Open Access
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Author(s): 
Stephen Poyer, Tanya Shewchuk, Catherine Goodman, et al.
Reference: 
Tropical Medicine & International Health, Volume 20, Issue 6, pages 744–756, June 2015

Eighteen months after WHO updated its case management guidelines, RDT availability remained poor in the private sector in sub-Saharan Africa.

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An Assessment of Participatory Integrated Vector Management for Malaria Control in Kenya

April 11, 2015 - 12:01 -- Open Access
Author(s): 
Clifford Maina Mutero, Charles Mbogo, Wolfgang Richard Mukabana, et al.
Reference: 
Environ Health Perspective

We comprehensively assessed experiences and findings on IVM in Kenya with a view to sharing lessons that might promote its wider application.

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