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Bio-efficacy and wash resistance of MAGNet long-lasting insecticidal net against wild populations of Anopheles funestus in experimental huts in Muheza, Tanzania

October 7, 2019 - 15:24 -- Open Access
Author(s): 
Eliningaya J. Kweka, Patrick K. Tungu, Aneth M. Mahande, Humphrey D. Mazigo, Subira Sayumwe, Shandala Msangi, Lucile Lyaruu, John Waweru, William Kisinza and James Wangai
Reference: 
Malaria Journal 2019 18:335, 1 October 2019

The decline in malaria cases and vectors is major milestone in fighting against malaria. The efficacy of MAGNet long-lasting insecticidal nets (MAGNet LLIN), an alpha-cypermethrin incorporated long-lasting net, with the target dose ± 25% of 5.8 g active ingredient (AI)/kg (4.35–7.25 g AI/kg) was evaluated in six veranda-trap experimental huts in Muheza, Tanzania against freely flying wild population of Anopheles funestus.

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Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine combinations for uncomplicated malaria in 10 sentinel sites across Ghana: 2015–2017

June 24, 2019 - 16:00 -- Open Access
Author(s): 
Benjamin Abuaku, Nancy O. Duah-Quashie, Lydia Quaye, Sena A. Matrevi, Neils Quashie, Akosua Gyasi, Felicia Owusu-Antwi, Keziah Malm and Kwadwo Koram
Reference: 
Malaria Journal 2019 18:206, 24 June 2019

Routine surveillance on the therapeutic efficacy of artemisinin-based combination therapy (ACT) has been ongoing in Ghana since 2005. The sixth round of surveillance was conducted between 2015 and 2017 to determine the therapeutic efficacy of artesunate–amodiaquine (AS–AQ) and artemether–lumefantrine (AL) in 10 sentinel sites across the country.

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NOT Open Access | Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia

February 6, 2019 - 15:31 -- NOT Open Access
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Author(s): 
Johannes Mischlinger, Paul Pitzinger, Michael Ramharter, et al.
Reference: 
Tropical Medicine & International Health Volume23, Issue9 September 2018, Pages 980-991

The LAMBA has higher validity than the sWHO and may therefore be preferable in resource‐limited settings without access to routine WBC‐evaluation.

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Severe Plasmodium vivax malaria, HIV, tuberculosis co-infection in a Sri Lankan traveller: case management and challenges during the prevention of malaria reintroduction phase

November 20, 2018 - 14:52 -- Open Access
Author(s): 
Dewanee Ranaweera, R. M. J. Kanchana Rajapaksha, Priyanganie Silva, Raja Hettiarachchi, W. M. Kumudu T. de A. W. Gunasekera, Hemantha Herath and Deepika Fernando
Reference: 
Malaria Journal 2018 17:429, 16 November 2018

It is important to consider comorbid conditions and immunosuppression when a patient with a benign form of malaria presents with severe manifestations.

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Dynamics of Plasmodium falciparum gametocyte carriage in pregnant women under intermittent preventive treatment with sulfadoxine–pyrimethamine in Benin

October 17, 2018 - 14:57 -- Open Access
Author(s): 
Sayeh Jafari-Guemouri, Jamila Dhiab, Achille Massougbodji, Philippe Deloron and Ndam N. Tuikue
Reference: 
Malaria Journal 2018 17:356, 11 October 2018

This study demonstrates that IPTp-SP treatment contributes to modify the parasite populations’ structure during pregnancy.

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Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies

June 5, 2018 - 14:38 -- Open Access
Author(s): 
Itziar Ubillos, Alfons Jiménez, Carlota Dobaño, et al.
Reference: 
Malaria Journal 2018 17:219, 1 June 2018

With this study, the immunogenicity profile of the WHO reference reagent, including seven immunoglobulin isotypes and subclasses, and more P. falciparum antigens, also those included in the leading RTS,S malaria vaccine, was better characterized.

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Targeted application of an organophosphate-based paint applied on windows and doors against Anopheles coluzzii resistant to pyrethroids under real life conditions in Vallée du Kou, Burkina Faso (West Africa)

April 4, 2018 - 14:52 -- Open Access
Author(s): 
Serge B. Poda, Dieudonné D. Soma, Roch K. Dabiré, et al.
Reference: 
Malaria Journal 2018 17:136, 2 April 2018

The combination of insecticide paint on doors and windows with LLINs yielded high mortality rates in the short term against wild pyrethroid-resistant malaria vector populations.

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Which intervention is better for malaria vector control: insecticide mixture long-lasting insecticidal nets or standard pyrethroid nets combined with indoor residual spraying?

August 22, 2017 - 17:41 -- Open Access
Author(s): 
Corine Ngufor, Josias Fagbohoun, Jessica Critchley, Raphael N’Guessan, Damien Todjinou, David Malone, Martin Akogbeto and Mark Rowland
Reference: 
Malaria Journal 2017 16:340, 16 August 2017

The use of chlorfenapyr and alpha-cypermethrin together as a mixture on nets (Interceptor® G2 LN) or a combined chlorfenapyr IRS and pyrethroid LN intervention provides improved control of pyrethroid-resistant malaria vectors by inducing significantly higher levels of mortality through the chlorfenapyr component and providing personal protection through the pyrethroid component.

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Intermittent preventive treatment of malaria in pregnancy: a cross-sectional survey to assess uptake of the new sulfadoxine–pyrimethamine five dose policy in Ghana

August 14, 2017 - 15:36 -- Open Access
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Author(s): 
Ivy Owusu-Boateng and Francis Anto
Reference: 
Malaria Journal 2017 16:323, 10 August 2017

The uptake of ≥3 doses of SP was high in the study area.

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First record of Anopheles stephensi in Sri Lanka: a potential challenge for prevention of malaria reintroduction

August 14, 2017 - 15:26 -- Open Access
Author(s): 
A. G. Gayan Dharmasiri, A. Yashan Perera, Jeevanie Harishchandra, Hemantha Herath, Kandasamy Aravindan, H. T. R. Jayasooriya, Gaya R. Ranawaka and Mihirini Hewavitharane
Reference: 
Malaria Journal 2017 16:326, 10 August 2017

Sri Lanka was certified as malaria-free by the WHO in September 2016, however, this new finding may pose a serious challenge to the efforts of the Ministry of Health to prevent the re-introduction of malaria transmission in the country, considering the role that An. stephensi could play in urban and high vulnerability areas of Sri Lanka.

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