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The World Health Organization (WHO)

Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia

October 19, 2016 - 17:24 -- Open Access
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Author(s): 
Takele Kefyalew, Zelalem Kebede, Prudence Hamade, et al.
Reference: 
Malaria Journal 2016 15:507, 18 October 2016

From the perspective of health workers, use of intramuscular artesunate as pre-referral treatment of severe malaria cases at the health post is possible but dependent on training and availability of skilled workers.

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Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

September 21, 2016 - 17:35 -- Open Access
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Author(s): 
Maru Aregawi, Samuel J. Smith, Musa Sillah-Kanu, John Seppeh, Anitta R. Y. Kamara, Ryan O. Williams, John J. Aponte, Andrea Bosman and Pedro Alonso
Reference: 
Malaria Journal 2016 15:480, 20 September 2016

The MDA achieved its goals of reducing malaria morbidity and febrile cases that would have been potentially diagnosed as suspected Ebola cases with increased risk of nosocomial infections.

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Rural and urban disparities in health-seeking for fever in Myanmar: findings from a probability-based household survey

August 1, 2016 - 10:15 -- Open Access
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Author(s): 
Tin Aung, Moh Moh Lwin, May Sudhinaraset and Chongyi Wei
Reference: 
Malaria Journal 2016 15:386, 25 July 2016

This study suggests that rural populations need improved access to trained providers.

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How important is the angle of tilt in the WHO cone bioassay?

May 2, 2016 - 06:28 -- Open Access
Author(s): 
Henry F. Owusu and Pie Müller
Reference: 
Malaria Journal 2016 15:243, 27 April 2016

The angle at which the test is performed significantly affects the amount of time mosquitoes spend resting on the nets, and subsequently mortality.

RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands

September 30, 2015 - 16:50 -- Open Access
Author(s): 
Nasserdine Papa Mze, Yaye Ndiaye, Daouda Ndiaye, et al.
Reference: 
Malaria Journal 2015, 14:373 (29 September 2015)

The utility of field-collected RDTs was validated as a source of DNA for genetic studies interrogating frequencies of drug resistance mutations, using two different molecular methods (PCR and High Resolution Melting).

Medical Treatment: 

Characterizing the insecticide resistance of Anopheles gambiae in Mali

August 25, 2015 - 06:07 -- Open Access
Author(s): 
Moussa Cisse, Chitan Keita, Raymond Beach, et al.
Reference: 
Malaria Journal 2015, 14:327 (22 August 2015)

Multiple insecticide-resistance mechanisms have evolved in An. coluzzii, An. gambiae s.s. and An. arabiensis in Mali.

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Medical Treatment: 

Cost of treating inpatient falciparum malaria on the Thai-Myanmar border

November 10, 2014 - 17:46 -- Open Access
Author(s): 
Shwe Kyaw, Tom Drake, Ronatrai Ruangveerayuth, Wirongrong Chierakul, Nicholas J White, Paul N Newton, Yoel Lubell
Reference: 
Malaria Journal 2014, 13:416 (29 October 2014)

This analysis finds no evidence for a difference in total admission costs for malaria inpatients treated with artesunate as compared with quinine.

Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort

June 10, 2014 - 12:36 -- Open Access
Author(s): 
Mosha D, Mazuguni F, Mrema S, Sevene E, Abdulla S, Genton B
Reference: 
Malaria Journal 2014, 13 :197 (27 May 2014)

Even with this caveat, a change of policy from quinine to AL for the treatment of uncomplicated malaria during the whole pregnancy period could be already envisaged.

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