The World Health Organization (WHO)
Last month there was great news for the malaria world: A detailed analysis of the impact of insecticide-treated bednets (LLINs), ACTs, and indoor residual spraying (IRS), showed that some 6.2 million deaths and 700 million cases were averted between 2000-2015, mostly since 2005. Add up the contribution of the vector control components, and it shows that 78% of all the gains originated from just these two tools: LLINs and IRS. Is it safe to draw the conclusion from this that vector control is and shall remain the integral and critical component that will lead us to a world without malaria by 2040? I think the answer to that is 'yes, very much so'.
Indoor residual spraying (IRS), the coating of interior walls of houses with insecticides, is common in malaria-endemic areas. While important in malaria control, IRS potentially exposes residents to harmful insecticides. The World Health Organization recommends steps to minimize exposure; however, no programme has focused on educating populations.
The population pharmacokinetic models developed for both AS/DHA and MQ showed a large variability in drug exposure in the investigated African paediatric population.
This is the first study to investigate the circulation of insecticide resistance alleles in An. arabiensis from Cabo Verde.
Outcome of pregnancy and infant survival were similar between treatment arms indicating that any of the four artemisinin-based combinations could be safely used during the second and third trimester of pregnancy without any adverse effect on the baby.
Data published by the World Health Organization (WHO) when evaluating Olyset+ as well of the study of Protopopoff et al. showed that much more permethrin is available on the surface of Olyset+ than on the surface of Olyset and the relatively small and rapidly dwindling dosage of PBO may have nothing to do with the superior effect of Olyset+.
Overall, coverage of both IPTp2+ and IPTp3+ has improved in recent years.
Adherence to guidance on malaria case management in EVD-affected countries was low at the height of the EVD epidemic in Guinea, and there was substantial malaria diagnostic testing in the absence of adequate PPE, which could have contributed to increased EVD transmission in the healthcare setting.
The C580Y finding from outside of the greater Mekong subregion supports the consensus to upscale molecular surveillance of artemisinin resistance outside of South East Asia.