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antimalaria agents

New imidazolidinedione derivatives as antimalarial agents

February 15, 2011 - 11:45 -- Kabogo Ndegwa
Author(s): 
Liang Zhang, Ramadas Sathunuru, ThuLan Luong, Victor Melendez, Michael P. Kozar, Ai J. Lin
Reference: 
Bioorganic & Medicinal Chemistry, Volume 19, Issue 4, 15 February 2011, Pages 1541-1549

A series of new N-alky- and N-alkoxy-imidazolidinediones was prepared and assessed for prophylactic and radical curative activities in mouse and Rhesus monkey models.

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