The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10109 malaria professionals are enjoying the free benefits of MalariaWorld today

antimalarial drug

A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

April 24, 2018 - 16:14 -- Open Access
Author(s): 
Isaie J Reuling, Lisanne A van de Schans, Teun Bousema, et al.
Reference: 
eLife 2018;7:e31549

The early appearance of gametocytes indicates gametocyte commitment during the first wave of asexual parasites emerging from the liver.

Medical Treatment: 

NOT Open Access | A Sleeping Area of Malaria Research Awakes

March 21, 2018 - 14:47 -- NOT Open Access
Tags: 
Author(s): 
Elizabeth A. Winzeler
Reference: 
Cell Host & Microbe, Volume 23, Issue 3, 14 March 2018, Pages 292–295

Phenotypic screening methods have had a profound impact on antimalarial drug development, but assays that predict which compounds might provide a radical cure have remained elusive.

Medical Treatment: 

CRIMALDDI: a prioritized research agenda to expedite the discovery of new anti-malarial drugs

November 14, 2013 - 09:53 -- Open Access
Author(s): 
Ward SA, Boulton IC
Reference: 
Malaria Journal 2013, 12 :395 (5 November 2013)
MalariaWorld

The CRIMALDDI Consortium has been a three-year project funded by the EU Framework Seven Programme.

Medical Treatment: 

Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum

May 3, 2012 - 08:01 -- Kabogo Ndegwa
Author(s): 
Theresa Dinio, Alexander P. Gorka, Andrew McGinniss, Paul D. Roepe, Jeremy B. Morgan
Reference: 
Bioorganic & Medicinal Chemistry, Volume 20, Issue 10, 15 May 2012, Pages 3292–3297

MalariaWorldPlasmodium falciparum, the deadliest malarial parasite species, has developed resistance against nearly all man-made antimalarial drugs within the past century.

Medical Treatment: 

Antimalarial drug interactions of compounds isolated from Kigelia africana (Bignoniaceae) and their synergism with artemether, against the multidrug-resistant W2mef Plasmodium falciparum strain

January 31, 2012 - 13:30 -- Kabogo Ndegwa
Author(s): 
Denis Zofou, Mathieu Tene, Pierre Tane & Vincent P. K. Titanji
Reference: 
Parasitology Research, Volume 110, Number 2, 539-544,

MalariaWorldFor decades, drug resistance has been the major obstacle in the fight against malaria, and the search for new drugs together with the combination therapy constitutes the major approach in responding to this situation.

Medical Condition: 
Medical Treatment: 

Open Access | Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications

August 24, 2011 - 10:11 -- Kabogo Ndegwa
Author(s): 
Mubjer RA, Adeel AA, Chance ML, Hassan AA
Reference: 
Malaria Journal 2011, 10:245 (21 August 2011)

This is the first study to report baseline information on the characteristics and implications of anti-malarial drug resistance markers in Yemen.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Resistance-mediating polymorphisms of Plasmodium falciparum among isolates from children with severe malaria in kumasi, ghana

February 22, 2011 - 07:59 -- Kabogo Ndegwa
Author(s): 
Abruquah H, Bio F, Tay S, Lawson B.
Reference: 
Ghana Medical Journal, Volume 44, Number 2

The study affirms Pfcrt as a better chloroquine resistance marker.

Country: 
Medical Condition: 
Medical Treatment: 

In Vivo and In Vitro Efficacy of Chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia

December 28, 2010 - 09:45 -- Kabogo Ndegwa
Author(s): 
H. Siswantoro, B. Russell, A. Ratcliff, B. Prasetyorini, F. Chalfein, J. Marfurt, E. Kenangalem, M. Wuwung, K. A. Piera, E. P. Ebsworth, N. M. Anstey, E. Tjitra, and R. N. Price
Reference: 
Antimicrobial Agents and Chemotherapy, January 2011, p. 197-202, Vol. 55, No. 1

Reports of potential drug-resistant strains of Plasmodium malariae in western Indonesia raise concerns that chloroquine resistance may be emerging in P. malariae and P. ovale.

Medical Condition: 
Medical Treatment: 

Imported Malaria in Finland 1995 to 2008: An Overview of Surveillance, Travel Trends, and Antimalarial Drug Sales (pages 400–404)

November 4, 2010 - 13:45 -- Kabogo Ndegwa
Author(s): 
Sandra Guedes, Heli Siikamki, Anu Kantele and Outi Lyytikinen
Reference: 
Journal of Travel Medicine, Volume 17, Issue 6, pages 400–404, November/December 2010

More efforts should be focused on disseminating pre-travel advice to immigrants planning to visit friends and relatives and travelers on self-organized trips.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Identification and Characterization of a Liver Stage-Specific Promoter Region of the Malaria Parasite Plasmodium

October 30, 2010 - 12:37 -- Kabogo Ndegwa
Author(s): 
Susanne Helm, Christine Lehmann, Andreas Nagel, Rebecca R. Stanway, Sebastian Horstmann, Manuel Llinas, Volker T. Heussler
Reference: 
PLoS ONE 5(10): e13653

During the blood meal of a Plasmodium-infected mosquito, 10 to 100 parasites are inoculated into the skin and a proportion of these migrate via the bloodstream to the liver where they infect hepatocytes.

Medical Treatment: 

Pages

Subscribe to RSS - antimalarial drug