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4-anilinoquinoline

4-Anilinoquinoline triazines: A novel class of hybrid antimalarial agents

January 25, 2011 - 08:55 -- Kabogo Ndegwa
Author(s): 
Ashok, Kumar | Kumkum, Srivastava | S., Raja Kumar | M.I., Siddiqi | Sunil K., Puri | Jitendra K., Sexana | Prem M.S., Chauhan
Reference: 
European Journal of Medicinal Chemistry, Volume 46, Issue 2, February 2011, Pages 676-690

A novel class of hybrid 4-anilinoquinoline triazines have been synthesized and evaluated in vitro for their antimalarial activity against CQ-sensitive 3D7 strain of P. falciparum as well as for their cytotoxicity toward VERO cell line.

Medical Condition: 
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