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polymerase chain reaction (PCR)

Malaria, a difficult diagnosis in a febrile patient with sub-microscopic parasitaemia and polyclonal lymphocyte activation outside the endemic region, in Brazil

November 14, 2013 - 10:01 -- Open Access
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Author(s): 
Brasil P, Costa AP, Longo CL, da Silva S, Ferreira da Cruz MF, Daniel-Ribeiro CT
Reference: 
Malaria Journal 2013, 12 :402 (7 November 2013)
MalariaWorld

A case of autochthonous Plasmodium vivax malaria with sub-microscopic parasitaemia and polyclonal B-cell activation (PBA) (as reflected by positive IgM and IgG serology for toxoplasmosis, cytomegalovirus, and antinuclear and rheumatoid factors) was diagnosed by polymerase chain reaction (PCR) after consecutive negative rapid diagnostic test results and blood films.

Open Access | Operational research to inform a sub-national surveillance intervention for malaria elimination in Solomon Islands

April 4, 2012 - 13:45 -- Kabogo Ndegwa
Author(s): 
Atkinson J, Johnson M, Wijesinghe R, Bobogare A, Losi L, O'Sullivan M, Yamaguchi Y, Kenilorea G, Vallely A, Cheng Q, Ebringer A, Bain L, Gray K, Harris I, Whittaker M, Reid H, Clements A, Shanks D
Reference: 
Malaria Journal 2012, 11:101 (30 March 2012)

MalariaWorldAn adaption to the malERA surveillance framework is proposed and recommendations made for a tailored provincial-level surveillance intervention, which will be essential to achieve elimination, and to maintain this status while the rest of the country catches up.

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Malaria Diagnostics: A Comparative Study of Blood Microscopy, a Rapid Diagnostic Test and Polymerase Chain Reaction in the Diagnosis of Malaria

April 4, 2012 - 06:53 -- Kabogo Ndegwa
Author(s): 
Iyabo T. Runsewe-Abiodun, Michael Efunsile, Beniam Ghebremedhin, Adetoun S. Sotimehin, Jerome Ajewole, James Akinleye, Brigite König, and Wolfang König
Reference: 
J Trop Pediatr (2012) 58(2): 163-164

MalariaWorldThe clinical diagnosis of malaria is challenging because its features mimic those of many other infectious diseases.

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Open Access | Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in Plasmodium vivax field isolates that failed chloroquine treatment

November 24, 2010 - 09:12 -- Kabogo Ndegwa
Author(s): 
Won-Ja Lee, Hyung-Hwan Kim, Yien-Kyoung Choi, Kyung-Mi Choi, Mi-A Kim, Jung-Yeon Kim, Jetsumon Sattabongkot, Youngjoo Sohn, Hyuk Kim, Jong-Koo Lee, Han-Sook Park, Hyeong-Woo Lee
Reference: 
Malaria Journal 2010, 9:331 (18 November 2010)

These results suggest that sequence variations in the DHFR-TS represent the prevalence of antifolate-resistant P. vivax in Korea.

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