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sulfadoxine

Not Open Access | Pharmacokinetic Properties and Bioequivalence of Two Sulfadoxine/Pyrimethamine Fixed-Dose Combination Tablets: A Parallel-Design Study in Healthy Chinese Male Volunteers

November 12, 2012 - 16:13 -- NOT Open Access
Author(s): 
Yan-Mei Liu, Kanyin E. Zhang, Chen Yu, et al.
Reference: 
Clinical Therapeutics, Volume 34, Issue 11, November 2012, Pages 2212-2220

MalariaWorldThe aim of the present study was to compare the pharmacokinetic profiles between a new generic and the branded reference formulation of sulfadoxine/pyrimethamine FDC tablets, and to assess the bioequivalence of the 2 products in healthy Chinese volunteers.

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Molecular assessment of dhfr/dhps mutations among Plasmodium vivax clinical isolates after introduction of sulfadoxine/pyrimethamine in combination with artesunate in Iran

December 16, 2011 - 14:30 -- Patrick Sampao
Author(s): 
Mandana Afsharpad, Sedigheh Zakeri, Sakineh Pirahmadi, Navid D. Djadid
Reference: 
Infection, Genetics and Evolution, Volume 12, Issue 1, January 2012, Pages 38-44

MalariaWorldIn conclusion, the present results suggest that SP could be effective in treatment against the erythrocytic stages of vivax malaria in Iran; however, the increased frequency of mutant haplotypes in Iran since 2006 is worrying and indicates the emergence of drug-tolerant/resistant P. vivax isolates in Iran in near future.

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Efficacy of intermittent preventive treatment with sulfadoxine–pyrimethamine on placental parasitemia in pregnant women in midwestern Nigeria

December 14, 2010 - 08:21 -- Patrick Sampao
Author(s): 
Michael E. Aziken, Kenneth K. Akubuo, Etedafe P. Gharoro
Reference: 
International Journal of Gynecology & Obstetrics, Volume 112, Issue 1, January 2011, Pages 30-33

To assess the effect of intermittent preventive treatment with sulfadoxine and pyrimethamine (IPT-SP) on placental parasitemia and maternal and perinatal outcome.

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Open Access | Synopsis: Sulfadoxine/Pyrimethamine Intermittent Preventive Treatment for Malaria during Pregnancy

October 26, 2010 - 11:39 -- Patrick Sampao
Author(s): 
Philippe Deloron, Gwladys Bertin, Valérie Briand, Achille Massougbodji, and Michel Cot
Reference: 
Emerging Infectious Diseases, Volume 16, Number 11–November 2010

The World Health Organization recently proposed conducting in vivo studies in pregnant women to evaluate molecular markers for detecting resistance precociously.

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