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Fungal and Parasitic Infections: T Cells but Not NK Cells Are Essential for Cell-Mediated Immunity against Plasmodium chabaudi Malaria

September 24, 2010 - 07:05 -- Patrick Sampao
William P. Weidanz, GayeLyn LaFleur, Andrew Brown, James M. Burns, Jr., Irene Gramaglia, and Henri C. van der Heyde
Infect. Immun., Oct 2010; 78: 4331 - 4340.

Collectively, these data indicate that the suppression of acute P. chabaudi infection by CMI is T cell dependent, is independent of NK cells, and may be attributed to the deficient IFN response seen early in T-cell-depleted mice.

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