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Open Access | Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

September 17, 2010 - 13:45 -- Patrick Sampao
Hunt P., Martinelli A., et al.
BMC Genomics 2010, 11:499 (16 September 2010)

Here, we combine in vivo experimental evolution, a rapid genetic strategy and whole genome re-sequencing to identify the precise genetic basis of artemisinin resistance in a lineage of the rodent malaria parasite, Plasmodium chabaudi.

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