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Reverse-benzamidine antimalarial agents: Design, synthesis, and biological evaluation

September 16, 2010 - 13:26 -- Patrick Sampao
Olivier Berger, Sharon Wein, Jean-Frederic Duckert, Marjorie Maynadier, Siham El Fangour, Roger Escale, Thierry Durand, Henri Vial, Yen Vo-Hoang
Bioorganic & Medicinal Chemistry Letters, Vol 20, Issue 19, 1 Oct 2010, Pg 5815-5817

In the frame of the development of bis-cationic choline analogs, the RSA of bis-N-alkylamidines were studied and a new series of reverse-benzamidine derivatives was designed.

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