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Bis-alkylamine quindolone derivatives as new antimalarial leads

September 15, 2010 - 13:41 -- Patrick Sampao
João L., Kaamil G., et al.
Bioorganic & Medicinal Chemistry Letters, Volume 20, Issue 19, 1 Oct 2010, Pg 5634-5637

Quindolone derivatives, designed to target the malaria parasite digestive vacuole and heme detoxification pathway, have been synthesized by reaction with 2-chloro-N,N-diethylethanamine.

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