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T cells

Fungal and Parasitic Infections: T Cells but Not NK Cells Are Essential for Cell-Mediated Immunity against Plasmodium chabaudi Malaria

September 24, 2010 - 07:05 -- Patrick Sampao
Author(s): 
William P. Weidanz, GayeLyn LaFleur, Andrew Brown, James M. Burns, Jr., Irene Gramaglia, and Henri C. van der Heyde
Reference: 
Infect. Immun., Oct 2010; 78: 4331 - 4340.

Collectively, these data indicate that the suppression of acute P. chabaudi infection by CMI is T cell dependent, is independent of NK cells, and may be attributed to the deficient IFN response seen early in T-cell-depleted mice.

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A retrospective evaluation of the role of T cells in the development of malaria vaccine

September 10, 2010 - 13:13 -- Kabogo Ndegwa
Author(s): 
Moriya Tsuji
Reference: 
Experimental Parasitology, Volume 126, Issue 3, November 2010, Pages 421-425

Due to the fact that the life cycle of malaria parasites is complex, undergoing both an extracellular and intracellular phases in its host, the human immune system has to mobilize both the humoral and cellular arms of immune responses to fight against this parasitic infection.

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