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bicyclic

Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity

September 6, 2010 - 09:14 -- Patrick Sampao
Author(s): 
Johanna Faist, Werner Seebacher, Marcel Kaiser, Reto Brun, Robert Saf, Robert Weis
Reference: 
Bioorganic & Medicinal Chemistry, Volume 18, Issue 18, 15 September 2010, Pages 6796-6804

Dialkylaminoalkyl derivatives of 2-azabicyclo[3.2.2]nonanes and of bicyclo[2.2.2]octanes were prepared and their activities determined in vitro against the multiresistant K1 strain of Plasmodium falciparum.

Medical Condition: 
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