Artemisinin derivatives are well-tolerated anti-malaria drugs that also exert anti-cancer activity. Here, we investigated artemisinin and its derivatives dihydroartemisinin and artesunate in a panel of chemosensitive and chemoresistant human neuroblastoma cells as well as in primary neuroblastoma cultures.
Biochemical Pharmacology, Volume 79, Issue 2, 15 January 2010, Pages 130-136, doi:10.1016/j.bcp.2009.08.013
Bioorganic & Medicinal Chemistry Letters, Volume 19, Issue 24, 15 December 2009, Pages 6914-6917, doi:10.1016/j.bmcl.2009.10.081
The growth inhibitory activity of imidazoquines, antimalarial imidazolidin-4-ones derived from primaquine, on human cancer cell lines HT-29, Caco-2, and MCF-7 has been evaluated.