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RDT

Open Access | Malaria rapid diagnostic tests: Plasmodium falciparum infections with high parasite densities may generate false positive Plasmodium vivax pLDH lines

July 12, 2010 - 14:50 -- Kabogo Ndegwa
Author(s): 
Maltha J, Gillet P, Cnops L, van den Ende J, van Esbroeck M, Jacobs J
Reference: 
Malaria Journal 2010, 9:198 (10 July 2010)

False positive Pv-pLDH lines in P. falciparum samples with high parasite density occurred in 6/9 P. vivax-specific RDTs. This is of concern as P. falciparum and P. vivax are co-circulating in many regions. The diagnosis of life-threatening P. falciparum malaria may be missed (two-band Pv-pLDH RDT), or the patient may be treated incorrectly with primaquine (three- or four-band RDTs).

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Open Access | Field and laboratory comparative evaluation of rapid malaria diagnostic tests versus traditional and molecular techniques in India

July 6, 2010 - 07:08 -- Kabogo Ndegwa
Author(s): 
Singh N, Shukla MM, Shukla MK, Mehra RK, Sharma S, Bharti PK, Singh MP, Singh A, Gunasekar A
Reference: 
Malaria Journal 2010, 9:191 (5 July 2010)

The results in this study show comparative performance between microscopy, various RDTs and PCR. Despite some inherent limitation in the five RDTs tested, First Response clearly has an advantage over other RDTs.

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Evaluation of rapid diagnostic tests for malaria case management in Gabon

November 13, 2009 - 15:39 -- Ingeborg van Schayk
Author(s): 
Denise Patricia Mawili-Mboumba, Marielle Karine Bouyou Akotet, Edgard Brice Ngoungou and Maryvonne Kombila
Reference: 
Diagnostic Microbiology and Infectious Disease, Article in Press, Corrected Proof

 

These tests should be considered as a good alternative to microscopy, allowing not only an efficient and rapid diagnosis of malaria in primary health facilities but also to aid in promoting changes for antimalarial prescription behavior.

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