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Review | Of mice and women: rodent models of placental malaria

July 22, 2010 - 09:16 -- Patrick Sampao
Lars Hviid, Claudio R.F. Marinho, Trine Staalsoe, Carlos Penha-Gonçalves
Trends in Parasitology, Volume 26, Issue 8, August 2010, Pages 412-419

Placental IE sequestration in the intervillous space is mediated by variant surface antigens (VSAs) selectively expressed in placental malaria (PM) and specific for chondroitin sulfate A (CSA). In Plasmodium falciparum, these VSAPM appear largely synonymous with the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family variant VAR2CSA.

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