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RDTs

Open Access | Evaluation of the Clearview(R) malaria pLDH malaria rapid diagnostic test in a non-endemic setting

September 29, 2011 - 08:16 -- Kabogo Ndegwa
Author(s): 
Sandrine Houze, Veronique Hubert, Dorit Pessler Cohen, Baruch Rivetz, Jacques Le Bras
Reference: 
Malaria Journal 2011, 10:284 (27 September 2011)

MalariaWorldThe Clearview(R) Malaria pLDH was efficient for the diagnosis of malaria. The test was very sensitive for P. falciparum and P. vivax detection. The sensitivities for P. ovale and P. malariae were better than other RDTs.

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Open Access | Strict adherence to malaria rapid test results might lead to a neglect of other dangerous diseases: a cost benefit analysis from Burkina Faso

August 10, 2011 - 08:21 -- Kabogo Ndegwa
Author(s): 
Bisoffi Z, Sirima SB, Meheus F, Lodesani C, Gobbi F, Angheben A, Tinto H, Neya B, Van den Ende K, Romeo A, Van den Ende J
Reference: 
Malaria Journal 2011, 10:226 (4 August 2011)

For RDTs to be preferred, a positive result should not influence the decision to treat a potentially severe NMFI with antibiotics. In the rainy season the presumptive strategy always remains the better choice for children.

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Open Access | Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

June 29, 2011 - 06:54 -- Kabogo Ndegwa
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Author(s): 
Ishengoma DS, Francis F, Mmbando BP, Lusingu JP, Magistrado P, Alifrangis M, Theander TG, Bygbjerg IC, Lemnge MM
Reference: 
Malaria Journal 2011, 10:176 (26 June 2011)

Although RDTs had low sensitivity and specificity, which varied widely depending on fever and parasite density, using RDTs reduced over-treatment with anti-malarials significantly.

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Open Access | Field trial of three different Plasmodium vivax-detecting rapid diagnostic tests with and without evaporative cool box storage in Afghanistan

June 23, 2011 - 14:08 -- Kabogo Ndegwa
Author(s): 
Mikhail AF, Leslie TJ, Mayan MI, Zekria R, Mohammad N, Hasanzai MA, Safi N, Whitty CJ, Rowland M
Reference: 
Malaria Journal 2011, 10:169 (22 June 2011)

Of the three RDTs, the CSPfPan test was the most consistent and reliable, rendering it appropriate for this P. vivax predominant region.

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Open Access | Prozone in malaria rapid diagnostics tests: how many cases are missed?

June 16, 2011 - 07:51 -- Kabogo Ndegwa
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Author(s): 
Gillet P, Scheirlinck A, Stokx J, De Weggheleire A, Chauque HS, Canhanga ODJV, Tadeu BT, Mosse CDD, Tiago A, Mabunda S, Bruggeman C, Bottieau E, Jacobs J
Reference: 
Malaria Journal 2011, 10:166 (15 June 2011)

Prozone occurs at different frequency and intensity in HRP-2 RDTs and may decrease diagnostic accuracy in the most affected RDTs.

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Open Access | "Test and treat" or presumptive treatment for malaria in high transmission situations? A reflection on the latest WHO guidelines

May 25, 2011 - 08:45 -- Kabogo Ndegwa
Author(s): 
Graz B, Willcox M, Szeless T, Rougemont A
Reference: 
Malaria Journal 2011, 10:136 (20 May 2011)

Recent WHO guidelines recommend a universal "test and treat" strategy for malaria, mainly by use of rapid diagnostic test (RDT) in all areas.

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Detection of malaria infection in blood transfusion: a comparative study among real-time PCR, rapid diagnostic test and microscopy

May 25, 2011 - 08:02 -- Kabogo Ndegwa
Author(s): 
Gholamreza Hassanpour, Mehdi Mohebali, Ahmad Raeisi, Hassan Abolghasemi, Hojjat Zeraati, Mohsen Alipour, Ebrahim Azizi and Hossein Keshavarz
Reference: 
Parasitology Research, Volume 108, Number 6, 1519-1523

The transmission of malaria by blood transfusion was one of the first transfusion-transmitted infections recorded in the world.

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Open Access | Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study

May 5, 2011 - 07:01 -- Kabogo Ndegwa
Author(s): 
Valerie D'Acremont, Judith Kahama-Maro, Ndeniria Swai, Deo Mtasiwa, Blaise Genton, Christian Lengeler
Reference: 
Malaria Journal 2011, 10:107 (29 April 2011)

Programmatic implementation of mRDTs in a moderately endemic area reduced drastically over-treatment with anti-malarials.

Open Access | Malaria diagnostic testing and treatment practices in three different Plasmodium falciparum transmission settings in Tanzania: before and after a government policy change

April 5, 2011 - 12:53 -- Kabogo Ndegwa
Author(s): 
Bastiaens GJ, Schaftenaar E, Ndaro A, Keuter M, Bousema T, Shekalaghe SA
Reference: 
Malaria Journal 2011, 10:76 (2 April 2011)

This study shows that an official policy change, where RDTs were provided and healthcare providers were advised to adhere to RDT results in prescribing drugs can be followed by more rational drug-prescribing behaviour.

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Open Access | Malaria rapid diagnostic kits: quality of packaging, design and labelling of boxes and components and readability and accuracy of information inserts

February 15, 2011 - 11:50 -- Kabogo Ndegwa
Author(s): 
Gillet P, Maltha J, Hermans V, Ravinetto R, Bruggeman C, Jacobs J
Reference: 
Malaria Journal 2011, 10:39 (13 February 2011)

Overall, malaria RDTs showed shortcomings in quality of construction, design and labelling of boxes, device packages, devices and buffers. Information inserts were difficult to read and lacked relevant information.

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