The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10493 malaria professionals are enjoying the free benefits of MalariaWorld today

PfMDR 1

Short Communication: Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue

July 19, 2010 - 12:01 -- Patrick Sampao
Author(s): 
Perri Pleeter, Jacqueline K. Lekostaj, Paul D. Roepe
Reference: 
Molecular and Biochemical Parasitology, Volume 173, Issue 2, October 2010, Pages 158-161

We utilize the recent successful overexpression of recombinant Plasmodium falciparum multi-drug resistance transporter, purification and reconstitution of the protein, and a novel high affinity chloroquine analogue to probe hypothesized interaction between the transporter and quinoline drugs.

Medical Condition: 
Subscribe to RSS - PfMDR 1