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artemisinin combination therapy (ACT)

Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout of malaria rapid diagnostic tests

July 5, 2012 - 14:31 -- Kabogo Ndegwa
Author(s): 
Masanja IM, Selemani M, Amuri B, Kajungu D, Khatib R, Kachur S, Skarbinski J
Reference: 
Malaria Journal 2012, 11:221 (2 July 2012)

MalariaWorldImplementation of RDTs increased use of RDTs for parasitological confirmation and reduced over-treatment with ACT during high malaria transmission season in one area in Tanzania.

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NOT Open Access | Pharmacokinetic Comparison of Two Piperaquine-Containing Artemisinin Combination Therapies in Papua New Guinean Children with Uncomplicated Malaria

May 15, 2012 - 12:02 -- Kabogo Ndegwa
Author(s): 
Sam Salman, Madhu Page-Sharp, Kevin T. Batty, Kaye Kose, Susan Griffin, Peter M. Siba, Kenneth F. Ilett, Ivo Mueller, and Timothy M. E. Davis
Reference: 
Antimicrob. Agents Chemother. June 2012 vol. 56 no. 6 3288-3297

MalariaWorldPharmacokinetic differences between piperaquine (PQ) base and PQ tetraphosphate were investigated in 34 Papua New Guinean children aged 5 to 10 years treated for uncomplicated malaria with artemisinin-PQ (ART-PQ) base or dihydroartemisinin-PQ (DHA-PQ) tetraphosphate.

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Open Access | Do patients adhere to over-the-counter artemisinin combination therapy for malaria? Evidence from an intervention study in Uganda

March 29, 2012 - 09:22 -- Kabogo Ndegwa
Author(s): 
Cohen JL, Yavuz E, Morris A, Arkedis J, Sabot O
Reference: 
Malaria Journal 2012, 11:83 (23 March 2012)

MalariaWorldOverall, adherence to subsidized ACT purchased over-the-counter was found to be moderate.

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Open Access | Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa

January 27, 2012 - 08:55 -- Kabogo Ndegwa
Author(s): 
Zwang J, Ndiaye J, Djimde A, Dorsey G, Martensson A, Karema C, Olliaro P
Reference: 
Malaria Journal 2012, 11:25 (25 January 2012)

MalariaWorldThe effects of AS&AQ on haematologic parameters were not different from those of other anti-malarial treatments used in sub-Saharan Africa.

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Open Access | District level external quality assurance (EQA) of malaria microscopy in Pakistan: pilot implementation and feasibility

February 23, 2011 - 09:48 -- Kabogo Ndegwa
Author(s): 
Khan M
Reference: 
Malaria Journal 2011, 10:45 (17 February 2011)

A district-based EQA, based on lot quality assurance methods was implemented, using context-specific operational guidelines, tools and training modules, and other inputs from the malaria control programme and partners.

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Open Access | An assessment of early diagnosis and treatment of malaria by village health volunteers in the Lao PDR

December 3, 2010 - 06:11 -- Kabogo Ndegwa
Author(s): 
Phommanivong V, Thongkham K, Deyer G, Rene JP, Barennes H
Reference: 
Malaria Journal 2010, 9:347 (1 December 2010)

VHVs' global EDAT performance is enhanced through training and monitoring. Persistent gaps in knowledge, care of patients and wrong treatment have to be addressed.

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